Moxibustion Combined With Clinical Research For Prozac Treatment Of Stroke Depression

Purpose:Post Stroke Depression,PSD is a secondary depression is a common complication of cerebral blood vessels. World Health Organization (WHO) also pointed out that mental illness is the major diseases of the21st century, mankind will be faced. Stroke depression (PSD), including a variety of psychiatric symptoms and somatic symptoms of complex emotional disorders. The major clinical manifestations as depression, sleep disturbance, decreased interest, fatigue, slow thinking, loss of appetite, pessimism and despair, even suicide attempts and behavior abnormalities and other symptoms. If timely diagnosis clinically and be an effective treatment can reduce patient morbidity and mortality, improve their quality of life. Western medicine treatment of the disease with5-HT reuptake inhibitors (SSRI), recognized as effective, but the drug there are side effects of digestion and nerve system, such as:nausea, vomiting, indigestion, lethargy, sexual dysfunction, etc., and expensive, difficult to accept patients, poor compliance. The Chinese treatment of the disease and delay the patient’s condition the development of some advantages. Designate the evidence of the Chinese variety of therapeutic means of treating stroke depression and efficacy of mechanism studies, has attracted universal attention from scholars. Which moxibustion for better treatment of the disease, no side effects, but the effect is faster, increasingly play to its advantages in the treatment of cerebrovascular disease.Treatment:Subjects from March2010to March2011, the subsidiary of Jiangsu Provincial Hospital of Nanjing University of Traditional Chinese Medicine neurology ward or out-patient and in accordance with patients with depression after stroke included in case standard, included in a total of60cases divided into two groups:treatment group and control group30cases.Treatment group moxibustion combined with fluoxetine in treatment, treatment control group to Prozac. The treatment group the moxibustion take back points Xinyu, liver Yu, spleen, Shenshu Ginger. Again to take Shenque mild moxibustion to enhance the function of the liver, spleen and kidney and slow down the common side effects of Prozac. In addition, the oral medication:reference drug instructions given Prozac maintenance dose oral2Omg/d, drugs in the early morning oral. Once a day,15times as a course of treatment, a total of3courses. Control group, oral drugs:in accordance with the therapeutic dose of the medication instructions to patients with oral drug Prozac, the first15days oral administration of20mg/d, later changed to40mg/d, drugs were administered in the morning oral. Once a day,15times as a course of treatment, a total of3courses. Result:1. Between the two groups after the t-test, P>0.05, no significant differences were comparable.2. Hamilton Depression Rating Scale:After treatment, the total efficiency by the X2test, although no significant difference in the treatment group the total efficiency (83.3%) than the control group (73.33%).3. Acupuncture treatment for depression after a stroke rating scale:After treatment, patients were to get a good effect, but the treatment group the total efficiency (86.66%) than the control group (66.67%). Therefore concluded that moxibustion combined with fluoxetine in treatment of PSD is better than single use of Prozac in the treatment of the PSD.4. TESS side effects scale:3courses after the end of the TESS score of the treatment group (3.7±1.5), the TESS score of the control group (15.8±4.4), score significantly higher than the treatment group (P<0.05). Therefore concluded that moxibustion can control and reduce the side effects of Prozac has brought, thereby improving the living conditions of the patients.Conclusion:Moxibustion combination of Prozac and the single use of fluoxetine in treatment of PSD can play a good effect, comparison between the two, moxibustion and drug combined with the efficacy of the treatment of PSD seems better, and from the short onset time andof a continuing nature and low side effects. Therefore, moxibustion and drug combination treatment of PSD is better than single drug therapy, and deserves wider application in the clinical.