TUPKP Versus TURP：a Meta Analysis

Objective To evaluate the efficacy and safety of bipolar transurethralplasma Kinetic prostatectomy（TUPKP） versus transurethral resection ofprostate（TURP）in treating benign prostate hyperplasia(BPH)．Methods Such online databases as Cochrane Library、Pub Med、EMbase、VIP、Wanfang and CNKI were searched by randomized controltrial（RCT）and prospective case controlled trial（CCT）about TUPKP vsTURP for the treatment of BPH．After study selection，assessment and dataextraction conducted, Meta analyses were performed by using the RevMan5.1software.Results Eight studies involving1418patients were included．Theresults of meta-analyses showed that：a）safety indicator：compared with theTURP，TUPKP group was significantly reduced hospital stay[WMD-1.17，95%CI(-1.90,-1.03) P＜0.00001],decrease in hemoglobin[WMD-0.85，95%CI（-1.27，-0.42）P＜0.0001], decrease in serum sodium[WMD-1.18，95%CI（-2.32，-0.05）P=0.04],catheter duration[WMD-25.88，95%CI（-36.25，-15.51）P<0.00001], postoperative irrigation time[WMD-8.93，95%C（I-10.20，-7.67）P<0.0001],transfusion rate[RR0.18，95%C（I-1.27，-0.42） P=0.0001],re-catheterization[RR0.39，95%CI（0.16，0.96） P=0.04],secondary hemorrhage[RR0.39，95%C（I0.16，0.96） P=0.04],andbladder neck contracture[RR0.41，95%C（I0.18，0.84）P=0.04]. b）efficacyindicator：In the aspect of IPSS, QoL, Qmax and PVR, there was nostatistically significant difference between two groups in the at1month,and TUPKP performed better at3,6and12months.Conclusion TUPKP is safe and effective procedure. It significantlyreduced the hospital stay, decrease in hemoglobin, decrease in serumsodium, catheter duration, postoperative irrigation time, transfusion rate,secondary hemorrhage, bladder neck contracture and better performance inthe follow up at3,6and12months.