| Purpose:Analyzing the otherness of TCM syndrome for Central Serous Chorioretinopathy (CSC) patient from different ages, course of disease and visual acuity by observing the CSC patients’ TCM syndrome as well as data from the Fundus Fluoreseseei Angiography (FFA), Optical Coherence Tomography (OCT) and syndrome information collected from clinical cases. Furthermore, contrastively studying the otherness between atypical and typical CSC and further analyzing the relativity between CSC and OCT.Method:Classifying the CSC cases, depending on three TCM syndrome types: Dampness on generic; Phlegm-damp becoming heat; Yin deficiency of liver and kidney, based on the CSC patients’ records in Jiangsu Traditional Chinese Medical Hospital from March to November of year2012. Classifying the data of FFA guided by<Fundus diseases (2nd Edition)>. Recording patients’ data such as medical history, systemic symptom, corrected visual acuity, FFA, OCT, etc.[Analyzing the otherness of TCM syndrome for Central Serous Chorioretinopathy (CSC) patient from different ages, course of disease and visual acuity; contrastively studying the otherness between atypical and typical CSC; further analyzing the relativity between CSC and OCT.Result:1. The CSC mostly occurs on the individuals of age1.41～50, the ratio of male and female patients is2.39/1. The distribution trend are similar for all ages;2. There is no significant differences in gender distribution. Of three syndromes, the Dampness on generic type patients are the oldest; the Phlegm-damp becoming heat type patients suffer longest syndromes and have worst vision acuity;3. There is no significant differences between ’typical’ and ’atypical’ group on gander distribution (P>0.05) but there are differences on the age (P<0.05), the ’atypical’ group is older than the typical one, and their average vision acuity is worse than the typical one as well (P<0.05). But there is no differences on the syndrome (P>0.05).4. For three groups:200～299μm,300-499μm,500-699μm, the average duration time for the1st group is longer than the other groups; the value of the average visual acuity has no statistically significant differences among the groups, but the1st group is much better than the groups less than200μm and larger than700μm. The thickness of central macular zone for the dampness on generic type patients mostly located at,300-499μm,500-699μm and over700μm groups; the phlegm-damp becoming heat type mostly located at smaller 200μm,200-299μm,300-499μm,500-699μm; the yin deficiency of liver and kidney type has no distribution in500-699μm, over700μm groups. The visual acuity of CSC are related to IS/OS (Sig<0.05).Conclusion:1. In this study, totally78patients, more than half of them are41to50years old, the ratio of men to women is2.39/1, the distribution of men and women in all ages are almost the same.2. TCM syndromes of CSC are divided into3different syndromes:dampness on generic type, phlegm-damp becoming heat type and yin deficiency of liver and kidney. There is no distribution difference between men and women in this3syndromes, but in the average age, the difference is significant. Yin deficiency of liver and kidney is the worst one on eyesight and course.3. There is no significant difference between of typical and atypical on course, but atypical patients always older than typical ones, and with poorer eyesight.4. Central macular thickness between200-299μm has longest duration. On eyesight, the thickness between200-299μm has the best eyesight, then less than200μm, more than700μm thickness is the worst one. Most dampness on generic type patients’central macular thickness are in3ranges:300-499μm,500-699μm and700μm; phlegm-damp becoming heat type are in all ranges, which thinner than700μm; yin deficiency of liver and kidney is mainly in thickness between500μm to699μm. We can see none of them exist in the range of thickness more than700μm. Inner segmentand outer segmentpho-toreceptor junction is associated with visual acuity. |
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