Impact Of Glucose And Lipid Metabolism And Situation Of Obesity And Medicine Of Type2Diabetic By Walking Exercise

Objective:In this paper, by walking exercise intervention in patients with type2diabeteslived in Hongkou District of Shanghai, explored the influence on the blood glucoseand lipid, and body position, aimed at improving the exercise intervention mode oftype2diabetes patients for urban communities.Methods:Screened86subjects by diabetic patients health and fitness status questionnaire,movement security investigation Questionnaire (PAR-Q), type2diabetes specialmedical examination and exercise stress test. Ruling out fasting hyperglycemia、serious complications and abnormal ECG display of exercise stress test. Developedindividualized exercise prescription based on assessment of their physical condition.Implemented walking exercise in the case of non-interference in the medication anddiet and other lifestyle. Allotted to the subjects involved in the exercise the pedometerand movement records to record daily activity (daily walking steps and one hour ofcontinuous steps), the subjective feeling (sleep and mental state) as well as the dailydiet and the medication status. Measurement and analysis of the subjects before andafter the exercise intervention, blood glucose and lipid, as well as comprehensivechanges in body mass index in the second and third medical examination and exercisestress test, carried out after3months and6months of exercise. The data wereanalyzed using SPSS18.0package.Results:After6months of aerobic walking exercise intervention group had fasting blood glucose levels decreased by6.68mmol/L to5.98mmol/L, p=0.002<0.01results havesignificant differences; While control group rose from6.00mmol/L to6.57mmol/L,p=0.007<0.01significant upward trend. Significant inter-group difference(p=0.005<0.01) between the intervention and control groups. Intervention group hadthe HbA1c level decreased from7.35%to6.38%after the intervention, a significantdifference by p<0.001; While the control group increased from6.75%to6.85%, nosignificant change in the level of HbA1c. Significant inter-group difference betweenthe intervention and control groups(p=0.003<0.01).Total cholesterol levels of the two groups showed increased to varying degrees,the intervention group was from5.03mmol/L increased to5.13mmol/L with nostatistically significant differences; While the control group was from4.88mmol/Lincreased to5.42mmol/L by the3rd month, p=0.006<0.05and increased again to5.64mmol/L by the6th month, p<0.001, both were with significantly increased.Significant inter-group difference between the intervention and control groups(p=0.002<0.01).The triglyceride level of intervention group decreased from1.82mmol/L to1.67mmol/L, but no significant difference; While the control groupincreased from1.60mmol/L to2.14mmol/L, with a significant upward trend(p=0.011<0.05), Triglyceride levels of the two groups of subjects were clearlydifferent, but the differences between groups reached the level of significance(p=0.05). By1.26mmol/L increased to1.47mmol/L, p=0.001<0.01significantlyelevated level of high-density lipoprotein intervention group; The control group wasfrom1.28mmol/L to1.40mmol/L had no significant difference in the two groups, butthe differences between groups did not reach a significant level (p=0.416>0.05). TheLDL level of intervention group decreased from3.02mmol/L to2.94mmol/L, but thedecline was not significantly different; While the control group from2.88mmol/Lincreased to3.29by the3rd month p=0.023<0.05, and then increased again to3.31mmol/L by the6th month, p<0.001, both were significantly increased. Significantinter-group difference between the intervention and control groups(p=0.001<0.01).BMI of the intervention group decreased from24.18to23.55, p=0.001<0.01with significant differences and to the range of the normal standards of the Chinesepeople by BMI less than24; While the control group still overweight (BMI>24).Waist-to-height ratio of intervention group subjects decreased from0.491to0.471,p<0.001with significant change; While control group from0.497to0.487, thedownward trend no statistically significant, the two sets of measurements with somedifferences, but not a significant difference between the groups (p=0.133>0.05).The number of taking no drugs in intervention group increased from5to9,accounting for28%of the total number of intervention group;The number of takingless drugs is10,accounting for31%of the total number.The number of taking nodrugs in control group decreased from9to4, accounting for13%of the totalnumber;The number of taking less drugs is6,accounting for19%of the totalnumber.No significant difference before and after the intervention about the kinds ofdrugs. The two groups taking for single or multiple use of sulfonamides andbiguanides, accounting for80~90%. Conclusions:After walking exercise for6months, the fasting plasma glucose, glycosylatedhemoglobin、lipids and the obesity status of subjects get a better control, proof of thewalk exercise is an effective means to control type2diabetes condition.