Research On Left Ventricular Function Change And Influence Factors Of Different Mitral Valve Lesions After Mitral Valve Replacement

Objective: In our study we analyzed patients with merely mitral valve replacement(MVR) surgery. The core theme was to relate left ventricular end diastolic diameter(LVEDD) and left ventricular ejection fraction (LVEF) with MVR. We observedpatients of two different pathological anomalies which comprise of mitral valveregurgitation and stenosis. Early decline of left ventricular function was identified afterMVR.Methods: From june2004to june2011,162cases were selected purely for (MVR).We split this group of patients into two categories comprising of73patients with mitralvalve regurgitation as Group Ⅰ and in GroupⅡthe patients with mitral valve stenosiswere allocated with total number of89patients. We further classified Group1on thebasis of LVEDD as: Group Ⅰ A with LVEDD≤55mm and Group ⅠA as LVEDD＞55mm. In order to compare postoperative results, preoperative data including LVEDDand LVEF was documented respectively. On the5th postoperative day, the abovementioned data was obtained by Echocardiography in order to compare and contrastwith preoperative numbers. We adopted ‘Paired t-test’ for the sack of pre andpostoperative comparison of patients belonging to same clause of disease. For thepatients belonging to the subgroup,‘Independent t test sample’ method was adapted todig down the differences that occurred postoperatively to LVEDD.Results: Patients who underwent MVR solely for mitral valve regurgitation had aremarkable postoperative decline in their LVEDD in comparison to preoperativeLVEDD （52.41±8.54mm vs.59.97±8.34mm, P<0.05. A conspicuous drop was alsoidentified in the LVEF in emulation between preoperative (56.52%±6.75%) andpostoperative data (49.45%±9.61%) with a p-valve <0.05. Individuals comprising the catalogue for mitral valve stenosis didn’t really end up with eminent variation of itsLVEDD when their preoperative (53.21%±6.01%vs.53.91%±6.42%,P>0.05） andpostoperative data (45.37±5.41mm vs.44.54±6.87mm， P>0.05) was compared.Differentiating between patients of mitral valve regurgitation with two subgroups as:Group Ⅰ A and GroupⅡB, show distinct drop in its postoperative LVEF with marginof decline of <0.01.Conclusions：1. Reduction in LVEDD after MVR in patients with Mitral Valve regurgitation.2. Tremendous early decline in LVEF in patients operated solely for mitral valveregurgitation as MVR.3. The early degree of decline in LVEF for patients with Mitral insufficiency afterMVR was related closely with the preoperative LVEDD.4. Patients with mitral valve stenosis undergoing MVR preserved their pre andpostoperative LVEDD and LVEF at the same level...