Analysis Of Surgical Treatment And Prognosis Of Intrahepatic Cholangiocarcinoma

Objective:To analyze identify prognostic factors after surgical management of intrahepaticcholangiocarcinoma (ICC).Methods:Clinical and pathological data of63patients who underwent surgery management forICC were analyzed，and were identified prognostic factors.Results:Median overall survival after surgical treatment of63ICCs was19months,1-,3-,and5-year overall survival was54%,25.4%, and12.7%, respectively.1,3,5year survivalrates of the radical resection were64.4%,35.6%,17.7%;1,3,5year survival rates ofthe palliative resection were40%,0%,0%;1,3,5year survival rates of the laparotomywere23%,0%,0%.Univariate analyses showed that Ca199increased, lymph nodemetastasis, distant metastasis, poor differentiation, JACC the higher the grade, thepalliative operation or laparotomy were associated with poor prognosis.COX multivariateanalysis showed that Ca199, the degree of tumor differentiation, operation mode is one ofthe factors affecting the prognosis of patients with the independent.Conclusions:The radical resection operation is the preferred treatment for ICC.Ca199increased, thedegree of tumor differentiation and operation mode of operation is independent indices inpatients with the treatment and prognosis.