Kidney Dehumidification Method Curative Effect Observation Of Early Treatment Of Knee Osteoarthritis

Objective:Through the experiment of randomized, prospective research design method, Evidence-based medicine treatment for kidney dehumidification method early knee osteoarthritis observed the clinical effect of the treatment of acute phase. In order to objectively observe and evaluate its clinical efficacy, safety, and clear the legislation on the treatment of clinical characteristics and advantages. For the legislation of the formulas provide reliable evidence of evidence-based medicine in clinical application.Methods:From Chinese academy of sciences wangjing hospital of traditional Chinese medicine orthopaedic outpatient service of60cases of early knee osteoarthritis. By using the computer random number table method. Two groups were randomly divided into experimental group and control group, In each group30cases. Randomized, prospective studies of experimental design methods, Will conform to the standard of patients according to the selected time according to the random order of table randomly into the treatment group and control group. Two groups were given1%2ml of knee joint cavity injection of sodium hyaluronate. Treatment group was given combined mentor clinical prescription of add and subtract, Traditional Chinese medicine decoction granules, A blunt, a dose of daily, two, for around1course of treatment, even take one course of treatment. Control group given joint non-steroidal anti-inflammatory drugs-ammonia sugar beautiful sheen enteric-coated metformin hydrochloride0.1g Po bid treatment, Around for1course of treatment, application1course of treatment. Respectively before treatment,2weeks and4weeks treatment, follow-up, A total of three time points, TCM syndrome score, VAS pain score, HSS knee function score. And evaluate effectiveness and safety, Statistics and analysis. Clear kidney spleen, benefit water dehumidification method for early knee osteoarthritis treatment effect, For the clinical popularization and application of the formulas to provide reliable evidence of evidence-based medicine.All the data with SPSS16.0statistical software:Metrics used mean+standard deviation percentage, counting index using cases and statistical description; Measurement data using t test and single factor variance analysis,(such as does not conform to normal distribution, then USES the rank and inspection). Count data by chi-square test.Results:By clinical experiment to observe the curative effect of the data, Treatment group before and after the treatment of patients with score comparison. The treatment group for VAS pain score before treatment(7.60±1.40), Score of HSS knee joint function (58.57±13.72); Treatment group after treatment for VAS pain score (2.40±1.19), Score of HSS knee joint function(83.93±6.66); The control group before and after the treatment of patients with score comparison. The treatment group for VAS pain score before treatment (8.17±1.32); Score of HSS knee joint function (56.10±10.79); Treatment group after treatment for VAS pain score (2.40±1.19); Score of HSS knee joint function(82.57±6.17). Joint pain between the two groups after treatment and the HSS function scoring after statistics analysis, Two weeks after treatment the treatment group and control group, no significant differences between, Not statistically significant, But from the degree of improvement, Control to improve the situation is better than that of the treatment group; There is statistical significance, Compare between the two groups. No obvious difference (P>0.05), Not statistically significant. TCM symptoms curative effect observation results show that:The treatment group30cases, The total effective rate was94.0%, The clinical control of0,26cases were markedly improved (86.67%), Effective in3patients (10.00%), Is invalid in3patients (3.33%); Control group30cases, The total effective rate was96.67%. Clinical control0cases,4cases were markedly improved (13.33%), Effective23cases (76.67%), Is invalid in3patients (10.00%). After statistics processing. Two groups show significant differences rate and total effective rate control (P<0.01), Description of TCM symptoms curative effect of treatment group and control group have significant differences. Statistically significant.Conclusion:Treatment group and control group in the treatment of knee osteoarthritis(Asthenia of both the spleen and kidney, wet type joints) Both have curative effect, Joint pain and improve function in treatment group and control group are no significant difference; But in improving TCM symptoms, Treatment group was better than control group, there are significant difference. Especially for joint swelling and effusion has distinct inhibition. Visible early kidney dehumidification method in the treatment of knee osteoarthritis(spleen kidney both deficiency, wet type joints) Has a unique advantage. Professor Zhang Hongmei evidence-based medicine in clinical. Early application of liuwei dihuang tonga subtraction treatment of knee osteoarthritis(Asthenia of both the spleen and kidney, wet type joints) Acute episodes. Clinical trial results suggest there is good curative effect.