| Purpose:Chronic hepatitis B in China is a common disease. The diseasehas become a major cause of cirrhosis and primary liver cancer, itstreatment of attention, This disease Western medicine is ananti-viral treatment, but only antiviral therapy can not completelyresolved liver inflammation. Abnormal liver function for liverinflammatory injury, if not treated, prone to cause liver fibrosison to develop cirrhosis of the liver. Liver protection andanti-inflammatory drugs on the market under various names differenteffects vary. This issue through the capsules contrast withGanlixin observe our hospital from pharmaceutical Baoganfugongwanefficacy of the treatment of chronic hepatitis B, and its advantagesin the treatment of chronic hepatitis B and not group to providenew ideas for the treatment of chronic hepatitis BMethod:1．Selection of casesIn this study,60patients were2O12.O6~2O13.02period inWuhan City Chinese Medicine Hospital of Hepatobiliary stomachoutpatient treatment to patients. Western medicine meet in2010theChinese Medical Association Hepatology, Infectious Diseases,Chinese Medical Association credits will formulate "chronic Hepatitis B Prevention Guide" diagnostic criteria. Patients werecorrectly antiviral treatment for more than1years, DNA hasnegative but abnormal liver function for more than1weeks.Thepatients were divided randomly into2groups of treatment andcontrol groups. The difference was not statistically significant,and comparable (P>0.05) compared to the two groups in age, sex,illness.2. Experimental methodsThe experimental method for the treatment group (30cases)given on the basis of conventional antiviral Baoganfugongwan pill10g three times daily treatment, The control group in conventionalantiviral therapy based on given Ganlixin capsules150mg threetimes a day treatment.4weeks for a course of12weeks totaltreatment.Observed before and after treatment in patients withclinical symptoms and liver function indicators adverse reactionsrecorded at the same time.3. Observed indexTherapeutic index: clinical symptom score, liver functionnormalization rate.Safety index: blood, urine, stool, kidney function, liver andgallbladder, spleen and pancreas ultrasound blood pressure, serumelectrolytes.4. Statistical analysisThe end of the experiment all statistical analysis of the datawere calculated using SPSS19.0statistical analysis software. Allstatistical tests were bilateral detected,P<0.05will beconsidered to test the discriminate statistically significant, P<0.01was considered significant statistical significance. Measurement data were presented as mean±standard deviation(±S) descriptive statistics, test of significance using t-test;count data using the X2test.Result:1.Comprehensive comparison: the treatment group,30casesmarkedly effective in16cases of12cases ineffective in2casesthe total efficiency of93.33%in the control group that wereeffective in16cases of10cases4cases total effective rate of86.67%, after rid it test, P<0.05Description excellent efficacyof the treatment group in the control group.2.Clinical comparison of TCM symptoms; treatment group, thetotal efficiency of93.33%in the control group, the totalefficiency of66.67%, chi-square test efficiency compared in thetwo groups of patients after treatment, a significant difference(P <0.01) treatment groups TCM symptoms efficacy advantages overthe control group.3.Efficacy of liver function: After treatment, ALT, AST weresignificantly decreased after the t-test showed a significantdifference (P <0.01) in the treatment between the two groups hadno significant difference (P <0.05) treatment in the two groups TBILdecline were statistically significant (P <0.05), the effect ismore pronounced in the treatment group (P <0.01) the ALB declinewere statistically significant (P <0.05) before and after treatment,no significant differences between the two groups (P>0.05).Compared to illustrate the Baoganfugong pills in Ganlixin improveliver function has the advantage.Security observation; treatment group,20patients were observedprocess no occurrence of adverse reactions, the control group with the prolongation of the observation time4patients significantgastrointestinal reactions. The Baoganfugong pill adversereactions were significantly below Ganlixin capsule.Conclusion: Baoganfugong pill with the antiviral treatment ofchronic hepatitis B clinical efficacy, TCM symptoms cansignificantly improve the clinical use of safety no adversereactions, and significantly improve patients’ quality of lifeshould be widely applied：... |
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