Outcomes And Tolerable Complications With The Use Of ESD For Upper GI Lesion

Background: Endoscopic Submucosal Dissection of early gastric cancer oresophageal cancer with no risk of lymph node metastasis was actuallydeveloped as a supplementary reliable tissue-retrieving endoscopicmanagement than EMR.ESD facilitate en bloc resection of the enjurymucosa in a more reliable manner, regardless of the mucosa.Methods: A prospective study was conducted from May2010to December2011in HUST (Tongji Hospital),125patients with age ranging to24-80years old were identified consecutively with EGCs or EECs.Results: We consecutively identified a total of125EGCs and EECs with thepatients who underwent ESD using the different Knifes. The studycomprised59(47.2%) male and66(52.8%) female; the mean age of allpatients was49.1years with extreme age between24-80years.Among the stomach lesions, we performed86ESDs,53female (61.1%) and33male (38.3%) with the p-value <0.00001a student s test was applied tocalculated this value. A p-value was0.03419<0.05statistically significantcompared to0.15as an estimation of the probability test.In the esophagus lesion, we also performed39ESDs, among26ESDs wereperformed in male (66.6%) and13female (33.3%). The average age was56.1year, the tumor size was1.06cm with a p-value <0.00001student stest was applied and no difference was found in both student test. The p- value was0.03982<0.05statistically significant compared to0.25as anestimation of recurrence and complication.Conclusion: Early screening lesion with endoscopy is the leading elementfor improving outcomes in patients with EGCs or EECs. ESD is practicablein our Hospital because it provides a precise histological diagnosis andremoves the lesion without cutting the GI tract; it s a safe and reliabletechnique.