| Objective To investigate the factors influencing the survival rate of patients with early gastric cancer undergoing endoscopic submucosal dissection,and to verify the guiding value of eCura scoring system for postoperative follow-up management of patients with EGC.MethodsTo retrospectively analyze the clinical data of 36 patients treated by ESD and pathologically diagnosed with early gastric cancer at the First Affiliated Hospital of Shihezi University from January 2009 to December 2015.ResultsThe study included a total of 36 EGC patients treated by ESD.The en bloc resection rate and complete resection rate of all lesions were 94.4% and 86.1%;The overall 1-,3-,and 5-year survival rates of all patients were 97.2%,97.2%,and 94.4%,and the tumor-specific survival rates at 1,3,and 5 years were 100%,100%,and 97.2%;The results of Cox regression univariate analysis showed that the lesion location and depth of invasion were the postoperative survival rates of EGC patients Influencing factors(P(27)0.1),of which lesion site was a protective factor(HR: 0.035,95% CI: 0.002 ～ 0.561)and depth of invasion was a risk factor(HR: 24.042,95% CI: 1.442 ～ 400.741).Multivariate analysis revealed no model that could be fitted.Conclusion1.EUS examination before ESD to evaluate the depth of lesion invasion is of clinical significance and practical value.2.Endoscopic screening for early gastric cancer is still required in people older than 70 years.3.The location of the lesion and the depth of invasion are the influencing factors of the postoperative survival rate of EGC patients,of which the depth of invasion is the risk factor and the location of the lesion is the protective factor.4.For patients with submucosal invasion depth ≥ 500 μm at the basal resection margin after ESD,close endoscopic follow-up is required when there are contraindications to surgery or refusal of additional surgery,CT and other examinations are performed without surrounding organ and lymph node metastasis,and eCura score is low. |
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