Clinical Research Of Tongbitang On Treating High-risk Diabetic Foot

Objective：To discuss the effect of High-risk diabetic foot which belonging to Qideficiency and blood stasis type treated by Tongbitang based on the theory of TCMcompared with Western medicine treatment group,study Tongbitang’s mechanism andpreliminary study the prescription’s mechanism.Methods：Choose60patients with High-risk diabetic foot lesions,and divided theminto treatment group(30cases)and control group (30cases) adopting experimental methodsof random and control.Under the same basic treatment,and Oral western medicine,whilethe Treatment group oral TCM compound. Twelve weeks was a course oftreatment.Before and after treatment we observed the changes of thesymptoms,signs,fasting plasma glucose (FPG),glycosylated hemoglobin(HbA1C), Anklebrachial index(ABI) and nerve conduction velocity,.T-test and X2test were used inprocessing data,and monitored the liver and renal functions.Results：Treatment group is more effective comparing with control group in thefollowing items:ABI(P<0.05), the MNCV and SNCV of the median nerve (P<0.01),theConduction speed of Phil. Total nerve and Phil. shallow neural of two groups both showsno obvious difference before and after treatment（P>0.05）.Conclusion：Tongbitang is functional for the treatment of High-risk diabetic footbelonging to Qi deficiency and blood stasis type,witch provides an effective and safemethod to treat diabetic foot with fewer side effects.