The Research On The Impact Factors Of Hospitalized Patients With Coronary Heart Disease Accompanying Depression Disorders

[Purpose] To explore the clinical status and impact factors of hospitalized patients with coronary heart disease and of the patients after Percutaneous Coronary Intervention accompanying depression disorders, we can explore the high risk factors in order to guide clinical early intervention.[Methods]1. Three hundred hospitalized patients with coronary heart disease were selected into the study in cardiovascular medical ward of Affiliated Hospital of Medical College from July2010to march2011, including143cases of men and157cases of women. All this patients underwent coronary artery CT or selective coronary angiography. One hundred and fifty patients after Percutaneous Coronary Intervention were selected into the study, including88cases of men and62cases of women.2. Use survey questionnaires-general situation questionnaire, Self-Rating Depression Scale and Hamilton Depression Rating Scale to assess the basic situation and depression state of all the participants.3. All statistical analyses were performed using SPSS version13.0. The measurement data between two groups were checked by t-test and the enumeration data between two groups were checked byχ2-test. Use logistic regression analysis to analyze single factor, then chose the factors which had statistically significant difference (P<0.05) for multivariate logistic regression analysis. Use Spearman multiple correlation analysis to evaluate the relationship between the Hamilton Depression Rating Scale symptomatic factors and the impact factors. [Results]1. There were148people accompanying depression disorders among the three hundred hospitalized patients with coronary heart disease (47.30%). Multivariate logistic regression indicated that the age (OR=-0.415, P<0.05, CI=0.443-0.984), smoking history (OR=0.384, P<0.05, CI=1.118～1.928),course of disease(OR=-0.250, P<0.05, CI=0.608～0.996),myocardial infarction(OR=0.676, P<0.05, CI=1.082～3.576),family history (OR=-0.744, P<0.05, CI=0.231～0.978) were related to coronary heart disease accompanying depression disorders. Multivariate correlation analysis indicated that anxiety factor and gender were closely related, weight factor and age, educational level, myocardial infarction had closed relationship, cognitive factors were closely associated with the course of disease, day and night changes were in relation to age, block factor and gender, age, education, drinking history, smoking history were related closely, sleep factor and gender, onset form, hypertension relations closed, despair factor have closed relationship with gender, age, educational level, course of disease.2. There were69people accompanying depression disorders among the one hundred and fifty patients after Percutaneous Coronary Intervention (46.00%). Compared with the non-depressive disorders group, the depressive group had more vascular lesions, more stents, higher cardiac function grading. Multivariate logistic regression indicated that the sex (OR=1.925, P=0.059, CI=0.958～3.869) hyperlipidemia(OR=4.910, P=0.012, CI=1.410～17.097), heart function classification (OR=3.004, P=0.003, CI=1.442～6.257) were related to patients after Percutaneous Coronary Intervention accompanying depression disorders.[Conclusion]1. The incidences of hospitalized patients with coronary heart disease accompanying depression disorders were higher.Age, smoking history, course of disease, myocardial infarction, family history were important risk factors of depression disorders in hospitalized patients with coronary heart disease. The Hamilton Depression Rating Scale’s seven symptoms factors are closely associated with multiple influence factors.2. The incidences of patients after Percutaneous Coronary Intervention accompanying depression disorders were higher. Sex, hyperlipidemia, heart function classification were important risk factors of depression disorders in patients after Percutaneous Coronary Intervention.