Clinical Study On The Effect Of Kidney-Nourishing And Phlegm-Resolving Method Combined With Lifestyle Adjustment Treating Obese Women With Polycystic Ovary Syndrome

Objective:Through this clinical research, to observe the clinical efficacy of Kidney-Nourishing And Phlegm-Resolving Method combined with lifestyle adjustment to cure the obese polycystic ovary syndrome (PCOS).Methods:Collect Kidney-Deficiency and Phlegm-Dampness type of obese women with PCOS patients, and randomize to two groups, the treatment group26cases, and control group22cases, respectively, to Kidney-Nourishing And Phlegm-Resolving Method combined with lifestyle adjustment, metformin combined with lifestyle adjustment, for three months of each therapy. Before treatment and after drug withdrawal, contrast the menstruation, TCM syndrome scores, body mass index (BMI), waist-hip ratio (WHR), serum luteinizing hormone (LH), follicle stimulating hormone (FSH), LH/FSH, testosterone (T), fasting plasma glucose (FPG), fasting insulin (FINS) level, Homeostatic model assessment (HOMA-IR),total cholesterol (TC),triglyceride (TG), high density lipoprotein (HDL-C), low-density lipoprotein (LDL-C), and other indicators during the treatment of basal body temperature (BBT)Results:The two groups significantly improved the menstrual cycle, the efficacy is no significant difference (P>0.05); the two groups could significantly improve the TCM syndrome, the treatment group’s markedly effective rate is53.85%, and the effective rate is88.46%, compared with the control group (markedly effective rate22.73%, effective rate81.82%), the efficacy is significantly different (P<0.05); in both groups significantly reduced BMI, WHR, treatment group to lose weight the effective rate of42.31%,76.92%efficiency, and the control group (effective rate59.09%,86.36%efficiency), efficacy is no significant difference (P>0.05); in the two groups significantly lower LH, LH/FSH ratio, T levels after treatment group there is no statistical difference (P>0.05); two groups can reduce the FINS and HOMA-IR levels, after treatment between the two groups of FINS is no significant difference (P>0.05), HOMA-IR is significantly different (P<0.05),in both groups lower blood TG, LDL-C, elevated HDL-C, groups after treatment are not statistically different (P>0.05),between the two groups there is no significant difference in the recovery of BBT biphasic(P>0.05). Two groups before and after treatment of FSH, the TC level, have no significant change (P>0.05), FPG level before and after treatment, has no significant change (P>0.05). Conclusion:Kidney-Nourishing And Phlegm-Resolving Method combined with lifestyle adjustment to cure the obese patients with PCOS, could improve patients’ menstrual cycle, TCM syndrome, weight loss, endocrine and the level of glucose and lipid metabolism and recovery BBT biphasic, the effect is exact, no significant adverse reactions, and the improvement of TCM syndrome, is better than metformin combined with lifestyle adjustment group.