The Clinical Observation Of Bu Yang Huan Wu Decoction Combined With Treatment Of Vascular Dementia

Objective:Observed Buyanghuanwu Decoction combined with the clinical efficacy and safety of the Western medicine treatment of vascular dementia. Some of the clinical reference value for the use of Chinese medical treatment method combined with Western medicine treatment of vascular dementia, and to explore an economical, safe, reliable efficacy, suitable for the treatment of vascular dementia.Methods:Selected60cases from the neurology outpatient and inpatient departments of a hospital in Wuhan City, included reference to the Chinese Medical Association neuropathy credits Vascular dementia diagnostic criteria for the draft and the2000Institute of Traditional Chinese Medicine Internal Medicine encephalopathy Professional Committee in2002by the "vasculardementia diagnosis, dialectic and efficacy criteria."Dementia indexing and efficacy according to the Clinical Dementia Rating Scale (CDR), Mini Mental State Examination (MMSE), the Blessed Behavior Scale (BBS), vascular dementia the dialectical Scale (SDSVD), daily behavior scale (ADL) assessment. Trial, randomized, single-blind control method,60cases were divided into treatment group and control group, n=30cases; the control group was treated with Western medicine nimodipine tablets, Huperzine A, oxiracetam tablets and rehabilitation training; treatment group on the basis of the control group Buyanghuanwu decoction. After8weeks of treatment, patients before treatment, cognitive function, TCM symptoms, daily capacity, neuropsychiatric symptoms for efficacy evaluation. And three conventional, liver, renal function and electrocardiogram periodically to evaluate the test security.Results:(1) After8weeks of treatment,60patients were off and removed the case, according to the program with the completion of clinical trials.(2) after8weeks of treatment in improving cognitive function, the evaluation of clinical efficacy, found that both groups improved the clinical symptoms (P<0.05), the total effective rate in treatment group increased significantly (P<0.05), with statistical significance.(3) after8weeks of treatment, before and after treatment of TCM syndrome score (SDSVD), as well as the BBS scale assessment show a significant difference (P<0.01) and between the two groups, treatment group and control group The difference was statistically significant (P<0.05), indicating that the treatment group than the control group to improve the effect of cognitive dysfunction is more significant.(4) after8weeks of treatment, before and after treatment the MMSE and the ADL scale score, P>0.05, no significant difference between the reality of the two groups, but the overall effective rate of treatment group was higher than that in the control group.(5) in terms of security, prescription, internal medicine and Western medicine were not found there are significant side effects on the human body.Conclusions:By the experimental observation, based on the use of Western medication, combined with traditional Chinese Yang Wu Tang and vascular dementia with rehabilitation training, with the exact effect. Can not only be more effective to improve cognitive impairment in patients, but also can improve the quality of life of patients, and no significant adverse reactions. Not only reflects the advantage of Integrative treatment of vascular dementia, and also develop a new approach for the clinical treatment of vascular dementia...