Research On The TCM Diagnosis And Treatment Regularity Of Ulcerative Colitis

Object:To study the relationship between traditional Chinese medicine (TCM) syndrome-typing of ulcerative colitis (UC) and some factors such as clinical symptoms, clinical classifications, severity of the disease, lesion range, stage, illness duration, characteristic of colorectal mucosa, and histological rank, thus to summarize the distinguishing feature of TCM syndrome-typing and the law of syndrome differentiation and treatment, and to make some clue for clinical diagnosis and treatment in future.Methods:Referring to "the Common Understanding of UC of TCM Diagnosis and Treatment " in the2009,a clinical observation table is designed.The data of totally110patients with UC is collected,sorted out,and added up. With SPSS17.0, the data is analyzed to investigate the regularity in following aspects,such as: age,clinical symptoms, clinical classifications, severity of the disease, the affected sites, stage, illness duration, characteristic of colorectal mucosa, and histological rank.Results:In this research, the proportion of male and female is1.12:1, and the average age is41.43±13.064.Large intestine damp-heat syndrome is especially common in UC, Spleen deficiency and damp accumulation, Liver depression and spleen deficiency, spleen-kidney Yang deficiency, cold-heat complicated, Yin-blood deficiency syndrome thereafter.Patients with lesion range in rectum and sigmoid colon are in the majority. Large intestine damp-heat syndrome occurs frequently in almost all the syndromes.In UC cases, initial type and chronic recurrent type are more common than chronic persistent type. And it also can be seen that damp-heat syndrome and spleen deficiency and damp accumulation syndrome are more common in initial and chronic recurrent types, and spleen-kidney Yang deficiency syndrome more common in chronic persistent type.In the aspect of disease severity, mild cases mainly express Large intestine damp-heat syndrome, Liver depression and spleen deficiency syndrome and Spleen deficiency and damp accumulation syndrome; moderate cases mainly express Large intestine damp-heat syndrome and Spleen deficiency and damp accumulation syndrome:severe cases mainly express Large intestine damp-heat syndrome and spleen-kidney Yang deficiency syndrome.It can be found that Large intestine damp-heat syndrome, Spleen deficiency and damp accumulation syndrome are more common in the group in which the illness course is less than5years; Spleen deficiency and damp accumulation syndrome is more common in the group in which the illness course is from5to10years; and spleen-kidney Yang deficiency syndrome is more common in the group in which the illness course is more than10years.The common manifestation of colorectal mucosa under endoscope is as follows: congestion and edema, vascular texture disorder, erosion and ulcer, secretion with pus, polyps, brittle texture, granulation, luminal stenosis, luminal shortening, and mucosal bridge.Congestion and edema, vascular texture disorder, erosion and ulcer, secretion with pus, and brittle texture are frequently found in Large intestine damp-heat syndrome and Spleen deficiency and damp accumulation syndrome; polyps in Large intestine damp-heat syndrome and Liver depression and spleen deficiency syndrome; and granulation however in Liver depression and spleen deficiency syndrome and Large intestine damp-heat syndrome. Each syndrome has its own manifestation of colorectal mucosa.There is no obvious relationship between TCM syndromes and mucosal and histological ranks. Rank II and Rank III are dominant in both mucosal rank and histological rank.Large intestine damp-heat syndrome and spleen-kidney Yang deficiency syndrome are more common in Rank III in both mucosal rank and histological rank.