The Study Of Bacterial Etiology In The Hospitalized Children With Pneumonia In Suzhou And The Antibiotic Resistance Investigation

Objective To investigate the bacterial pathogens in children with pneumonia andanalysis the antibiotic resistance of these bacteria in Suzhou.Methods Date of sputum specimen of8179hospitalized childhood patients withpneumonia from October2005to September2011were collected. The incidence ofpositive bacteria and the rate of resistance to different antibiotics were calculated.Results About29.23%of total8179cases were infected with different bacteria. Themost common pathogens were Streptococcus pneumoniae (SP)42.40%(1082/2552)、Haemophilus influenze (HI)14.81%(378/2552)、Moraxelle catarrhalis (MC)11.01%(281/2552)、Staphylococcus aureus (SA)8.50%(217/2552)、Escherichia coli (E.coli)5.02%(128/2552)、Pseudomonas aeruginosa (PA)4.86%(124/2552)、Klebsielliapneumoniae (KPN)4.23%(108/2552)、Acinetobacter baumanni (iAB)2.82%(72/2552)、Enterobacter cloacae2.08%(53/2552)、 Haemophilus parainfluenzae (PHI)2.04%(52/2552) and others2.23%(57/2552). The infection rate of different bacterium wasrelated with age、season and the type of pneumonia. SP infection was most frequentlydetected, besides this, MC infection was more frequent in olders, the younger ones werelikely to be infected by HI、SA and E.coli. HI infection was more frequent in summer andMC in winter. Sever pneumonia has the highest bacterial infection rate in the differenttypes.2140bacteria had the susceptibility test, all their antibiotic drug resistance isincreasing. SP and SA are mainly resistant to penicillin、erythromycin and clindamycin. HIhas the highest resistance70.65%to SMZ-TPM, the next is35.48%to ampicilin. E.coliand KPN have high resistance to all the sefacin、ampicilin and cidomycin, but sensitive to amikacin. PA has more antibiotic strains in the past three years, especially to cefotaxim andpipracil.Conclusions Streptococcus pneumonia and Haemophilus influenze are the mostcommon pathongens in children with pneumonia. The positive rate of different bacteriumwas related with age、season and the type of pneumonia. We should keep an eye on theantibiotic drug resistance phenomenon in order to reduce the increasing antibiotic drugresistance rate.