Analysis Of The Formation Of Etiology And Clinical Features Of The Ascites

Background: Complex causes the formation of ascites, a lot of difficultiesfor the clinically identification of benign and malignant ascites. For theclinical diagnosis of unexplained ascites, especially in the early diagnosis ofmalignant ascites is still a clinical problem.Objective: Retrospectively analyzed the clinical characteristics of397cases to ascites reasons unknown and201cases of hypoproteinemia as the mainpredisposing factor in patients with ascites in ascites and serum albuminquantitative correlation. For the majority of clinical health care workers canprovide more information to identify aspects of benign and malignant ascitesreference and diagnostic thinking.Methods: Retrospective analysis of patients who were admitted to thewards of the First Hospital of Jilin University, from March1,2005to March1,2011, select the ascites reason were all unknown in patients with a total of397cases and analysis of clinical data; other select clear clinical diagnosis of thistime admitted of201cases of simple chronic hepatitis and the nephroticsyndrome patients, including103cases of chronic hepatitis,98cases ofnephrotic syndrome patients, get the quantitative correlation of ascites andserum albumin by statistical methods.Results:This study,397cases of patients with ascites of unknown, the clinicaldiagnosis of malignant tumors is the largest proportion (42%), followed is thecirrhosis (18%), and the third is tuberculous peritonitis (17%), gastrointestinaltumor in the malignant ascites is the most common (28%). In the analysis thequantitative between the ascites and albumin, the results suggest that patients with chronic hepatitis alone albumin prone to ascites less than25.65g/L;nephrotic syndrome, hypoproteinemia group, easy-to-ascites albuminquantitative20.60g/L; the detection value of the ascites ADA and LDH intuberculous peritonitis increased significantly; the serum tumor marker testresults suggest that serum tumor markers of serum CA199, CEA, AFP in themalignant group and the cirrhosis group, tuberculous peritonitis group, thedifference was statistically significant, indicating that it is usefull to thediagnosis of benign and malignant ascites, and serum CA125among the threegroups, the difference was not statistically significant.Conclusion:1, In this study, the top three of the cause of unexplained ascites aremalignancy, liver cirrhosis and tuberculous peritonitis, where the minimum ageof onset is tuberculous peritonitis group.2,Ascites ADA and LDH can be a certain degree of help for theidentification of the benign and malignant ascites.3, The detection of serum tumor markers of serum CA199, CEA, AFP can be acertain sense for the diagnosis of benign and malignant ascites，however, thedetection of serum CA125does not make sense in the diagnosis of benign andmalignant ascites.4, As the chronic hepatitis,and nephrotic syndrome,for example, get thequantitative correlation of ascites and serum albumin, the results suggest thatsimple chronic hepatitis serum albumin less than25.65g/L prone to ascites;nephrotic syndrome group easy-to-ascites when the quantitative serum albuminlow than20.60g/L.