The Research Of Anterior-posterior Chemical Composition And Activity Of Processing Gingseng And Mongolian Milkvetch Root | Posted on:2013-02-07 | Degree:Master | Type:Thesis | Country:China | Candidate:X G Zhao | Full Text:PDF | GTID:2214330374960261 | Subject:Pharmacognosy | Abstract/Summary: | PDF Full Text Request | purpose:Adopting adequate processing methods to modify the active component orcontent of ginseng and mongolian milkvetch root, at the same time letting them possess better orcertain especial curative effect to develop new drugs or correlated health product.They couldnot only satisfy clinical medication demand and ever-increasing healthcare requirement,butpromote sustainable development of traditional Chinese physician and traditional Chinese medicineenterprise.methods:Apply physical chemistry methods of high temperature and high pressure toelaborate the dried medicinal herb of ginseng and mongolian milkvetch root.Study the qualitycriteria of processed product and crude drug in accordance with The Pharmacopoeia of thePRC;apply ultraviolet spectrophotometry,high performance liquid chromatography and electrospray massspectrography to carry out qualitative analysis and quantitative analysis of active component in theabove-mentioned Materia Medica and to investigate variation of active component in the bothChinese herbal drugs via especial processing methods;according to the investigationconsequence,we select material medica to undertake pharmacology study and cell biology studydirectly.consequence:The finding of quality criteria of dried medicinal herb and processed productof ginseng and mongolian milkvetch root is in line with the regulation of The Pharmacopoeia ofthe PRC on the whole; carry out qualitative analys is and quantitative analys is of active component ofthe both processed product,we could find that natural saponins component degrades into Rg3andsome scarce ginseng saponins component by utilizing different processing methods bydegrees in the processed ginseng and the glycoside of mongolian milkvetch root receives obviousimprovement; prove that processed ginseng have no toxicity though doing pharmaco-experiment and demonstrate that the both traditional Chinese medicine processed improve immunologicenhancement by cell in vitro,however,their anti cancer effect is not obvious.What's more, mongolian milkvetch root have motivating multiplication effect of cancer cells.conclusion:Change the alteration of the active component effectually after elaboratingby special processing methods of ginseng and mongolian milkvetch root.At equal pace,they possess special drug action.And in comparison with quondam crude drug,we did not find ill-effect. | Keywords/Search Tags: | ginseng, mongolian milkvetch root, processing, active component, activity research | PDF Full Text Request | Related items |
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