| BackgroundStroke lead to great economic and disease burdens for individuals and society because of its high fatality and disability rate, clinical characteristics and their effects on prognosis are probably different for different subtypes of acute stroke.ObjectiveThe aims of this study were to compare difference in risk factors between different subtypes of stroke, and to examine the associations between risk factors and in-hospital prognosis, so as to provide scientific basis to lower the case fatality and disability rate.MethodsAcute cerebral infarction, intracerebral hemorrhagic and subarachnoid hemorrhage patients in six hospitals in Tongliao city, Inner Mongolia, from January 1, 2003 to December 31, 2005 were included in the present study. Demography characteristics, life style factors, medical history, BP levels, clinical laboratory tests, imaging data and clinical outcomes during hospitalization were collected using a standard questionnaire by trained staffs from medical records. Statistical analysis was conducted using SPSS16.0 statistical software. Comparisons of risk factors between three subtypes of stroke and baseline characteristics at admission between the patients with different outcomes for each subtype of stroke were conducted. The odds ratios (ORs) and 95% confidence interval (95% CI) of study outcomes among patients with different baseline characteristics were calculated by using multiple logistic models, and linear tendency tests were conducted. Results1. A total of 3 938 stroke patients including 2 178 acute cerebral infarction, 1 604 intracerebral hemorrhagic and 156 subarachnoid hemorrhage patients were included in the analysis. There are some differences in demography characteristics, life style factors, medical history and clinical laboratory tests between the subtypes of stroke.2. The mortality is lower in acute cerebral infarction patients than that in intracerebral hemorrhagic and subarachnoid hemorrhage patients (1.79%, 5.86%, 5.77%), P<0.05. The rate of disability for cerebral infarction was the highest (41.32%), followed by that of intracerebral hemorrhagic (37.18%), and the rate of disability for subarachnoid hemorrhage was the lowest (6.41%), P<0.05.3. For cerebral infarction patients, multivariate-adjusted ORs of death for male, physical workers, and patients with history of diabetes, history of renal disease, heart rate and FPG were 7.158(3.378,15.170),16.592(2.089, 31.793),13.840(2.109,90.820), 9.274(1.021,84.222), 1.075(1.024,1.129) and 1.382(1.162,1.644), respectively, all P<0.05; multivariate-adjusted ORs of disability for patients with history of hypertension and SBP were 1.399(1.073, 1.824) and 0.994(0.990, 0.999), respectively, all P<0.05.4. For intracerebral hemorrhagic patients, multivariate-adjusted ORs of death for physical workers, history of cerebral infarction, SBP, DBP, heart rate and FPG were 0.515(0.328,0.808), 5.154(2.089,12.710), 1.019(1.013,1.025), 1.022(1.011,1.033), 1.030(1.017,1.044) and 1.413(1.139,1.753), respectively, all P<0.05; multivariate-adjusted ORs of disability for SBP and DBP were 1.007(1.001,1.013) and 1.016(1.005,1.028), respectively, all P<0.05.5. For subarachnoid hemorrhage patients, multivariate-adjusted ORs of death for heart rate was 1.085(1.015,1.159), P<0.05; multivariate-adjusted ORs of disability for the Mongolian and age were 2.065(1.035,20.953) and 1.126 (1.014,1.250), respectively, all P<0.05.Conclusion1. The distribution of baseline characteristics and short-term clinical outcomes were different among cerebral infarction, intracerebral hemorrhagic and subarachnoid hemorrhage patients. 2. Physical work, history of diabetes, history of renal disease, history of hypertension, elevated heart rate and increased FPG were risk factors of poor prognosis for cerebral infarction patients.3. Intellectual work, hypertension, elevated heart rate and increased FPG at admission were risk factors of poor prognosis for intracerebral hemorrhagic patients.4. Elevated heart rate and old age were risk factors of poor prognosis for subarachnoid hemorrhage patients; the risk of poor outcome was higher in Mongolian patients than in Han patients. |
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