The Clinical Observation Of Wind Evil Encroach Lung-type Upper Airway Cough Syndrome That Treatment Of Modified Ke Ping Tang

Objective:To observe the effect of treating Wind evil encroach lung-type upper airway cough syndrome because of allergic rhinitis with "modified Ke Ping Tang" united conventional treatment of western medicine and western medicine treatment,comparison of the two effects, With the effects of substance P.Discussion of Chinese medicine treatment of upper airway cough syndrome General advantages. Evidence-based medicine perspective to clarify the mechanism of the side for future clinical use of lay the foundation for the promotion.Information and methods:1. Selection wind cough disease traditional Chinese medicine belong to Wind evil encroach lung-type, and Reference to Western diagnostic criteria of UACS because of allergic rhinitis, Select 66 cases of patients, and according to traditional Chinese medicine dialectical standard classification for randomly divided into traditional Chinese and western medicine and western medicine treatment.The last corresponding is 63 cases,with treating group 32cases,control group 31cases.2. Both groups were given four compound liquorice tablets,oral tid, loratadine tablets 10mg oral qn,montelukast tablets lOmg oral qn.Treatment group at the foundation of western medicine on the use of add "modified Ke Ping Tang" with the treatment of cough, Compared clinical efficacy of the two groups, Detection of two groups before and after treatment in the substance P.Five days after treatment, the first ten days of cough, detection the decreased level of statistical groups. In the course of four weeks after the end of follow-up cases of recurrence of the number of cases cured.3. Statistical treatment:SPSS13.0 statistical software used for the United States the results of statistical treatment, Set for P≤0.05 statistically significant difference. (1) pre-treatment comparability analysis (2) Group matching t test before and after treatment (3) Group into a group t test (4) Comparison of the rate of adoption of the U test.Results:1. Clinical Observation:Comparison of TCM Syndromes points and General efficacy, The two groups before and after treatment within each group of points compared syndrome were significantly statistical significance (P<0.01),Two groups before and after treatment comparison points TCM Syndrome have decreased significantly. The two groups after treatment of TCM Syndrome margin points and difference between two points were no significant differences (P>0.05), Two groups of traditional Chinese medicine syndromes in reducing no significant difference in points. And there General effects of the two groups was no significant difference statistically significant(P>0.05), General effects of the two groups no significant difference (P> 0.05),. The efficiency of the two groups after treatment significantly higher than those of comparison group slightly.2. The intervention of "modified Ke Ping Tang" on the substance P:Compared the two groups before and after the treatment group, substance P.Two groups after treatment and difference after treatment were all significant differences (P<0.01).Lower level of substance P treatment group was significantly better than the control group.3. Two groups of recurrence after treatment follow-up compared to the situation:Cured two groups of recurrence after four weeks follow-up compared to the situation there is statistically significant difference (P<0.05), The number of recurrent cases of the treatment group fewer than the control group.4. Two groups of patients found no obvious side effects during the trial group, but three cases have one week off treatment.Conclusion:1. Improvement of TCM Syndromes points and General aspects of efficacy to determine, after ten days the treatment of TCM Syndrome General effects of integration. The two groups had no significant difference, but follow-up cases of recurrence of the number of cases cured at four weeks after the end of treatment, Western medicine treatment of simple cases of the control group recurrence was significantly more than the treatment group, Description that help with The Chinese medicine Wind evil encroach lung-type upper airway cough syndrome because of allergic rhinitis treatment effective, And a significant reduction in recurrence rate after cessation of medication.2. Cough efficacy of single symptoms in the treatment of 5 days, experimental group was significantly better than the control group (P<0.05), and the two groups at 10 days,treatment group was significantly better than the control group (P<0.05), the experimental group in alleviating the cough symptoms, the onset time is short, rapid onset of cough relief was the experimental group better than the control group.3. A significant reduction in the substance P. The treatment group was significantly better than the control group, western medicine alone. Description that "Modified Ke Ping Tang" to reduce inhibition of cytokines involved in the pathogenesis and reduce airway inflammation there is synergy maybe are one of the mechanisms of Qufeng Xuanfei, Tongqiao Huatan traditional Chinese medicine.4. Four weeks after the end of treatment, cough cure rate of cases of recurrence, recurrence in the control group significantly more than the number of test groups, test group better than the control group (P<0.05). 5. "Modified Ke Ping Tang" has obvious security and effective in clinical application.