Qbiective: Through the invigorating spleen removing dampness removing toxin and vigoration of blood circulation treatments, to oral medicine treatment for 3 months , Observation for chronic viral hepatitis patients liver merger pre-diabetes and diabet- es phase of clinical curative effect , And discuss the mechanismMethods: Through the invigorating spleen removing dampness removing toxin and vigoration of blood circulation treatments, to oral medicine treatment 64 cases of patients with hepatitis b virus square liver disease patients with secondary glucose metabolic disorder for 3 months ,according to the illness is divided into patients with hepatitis b virus chronic liver disease increased risk of diabetes type and the subsequent liver secondary diabetes HBV virus two groups. Through the system of clinical data including survival quality investigation for TCM therapy reduced glucose metabolic disorder of effect is analyzed ,finish the invigorating spleen removing phlegm rem- oving toxin and elimination of blood stasis treatments for chronic viral hepatitis patients liver concurrent glucose met- abolic disorder clinical research .Result: Patients with hepatitis b virus chronic liver disease increased risk of diabetes type total effectiveness of clinical 83% .Among them powerfully 22 cases effectiveness, 3 cases effectiveness and 5 cases. Improving TCM symptoms, including the total effective rate 100% got 16 cases marked effectiveness, 14 cases, invalid 0 case. ALT, AST, GGT, ALB, GLU TBIL, 2hGLU, INS, 2hINS, compared with before treatment decreased obviously, there is significant difference (P < 0.01). Insulin sensitivity index increased significantly, insulin resistance index declined obviously, there is significant difference (P < 0.01); Patients with hepatitis b virus chronic liver disease, secondary diabetes total effectiveness of clinical 67.6%, including < 10 cases, effectively 13 cases, invalid (11). Improving TCM sym- ptoms, including the total effective rate 100% effective got 17 cases, 13 cases, invalid 0 case. After the treatment of TCM symptom scores significantly lower than before treatment, have very significant difference (P < 0.01).ALT, AST, GGT, TBIL, GLU, 2hGLU, INS, compared with before treatment 2hINS reduced significantly (P < 0.01); Insulin sensitivity index increased significantly, insulin resistance index dropped significantly, compared with before treatment there are very significant difference (P < 0.01). Two groups in eight dimensions of quality of life than: before treatment and physiological function improved obviously, there is difference (P < 0.05). Physiological role restrictions, physical pain and emotional character limit significant decrease, have significant difference (P < 0.01). General health and vigor, social function and mental health significantly improve, there is significant difference (P < 0.01).Conclusion: the invigorating spleen removing dampness removing toxin and vigoration of blood circulation treatments can effectively improve the chronic viral hepatitis patients liver secondary glucose metabolic disorder, repair liver function, reduce blood sugar, raise insulin sensitivity, improve the clinical symptoms and signs, improve the quality of life. |