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Semi-automatic Chemiluminescence Immunoassay System

Posted on:2012-01-19Degree:MasterType:Thesis
Country:ChinaCandidate:R J ZhangFull Text:PDF
GTID:2212330338466079Subject:Biomedical engineering
Abstract/Summary:PDF Full Text Request
Chemiluminescence Immunoassay chemiluminescent reaction is combined with the immune response generated a promising immune analysis. It uses micro doubling technology,with high sensitivity,coupled with antigen-antibody reaction, the specificity is also very good, the reagents used are safe, stable, cheap, very wide detection range, from the traditional protein, hormones, enzymes and even the drugs were could be detected, the diagnosis of disease provides a powerful diagnostic tool. China in recent years chemiluminescence immunoassay analyzer and other related products are in development stage, the paper products for the domestic situation, reference to foreign products and technologies related to the semi-automatic chemiluminescent immunoassay analyzer for the overall design and research.System uses antibody or antigen coated magnetic beads as the solid phase carrier, luminol derivatives(ABEI) labeled with different antibodies or antigen as a liquid carrier, after the separation of washing, The chemiluminescence reaction in H2O2 Alkali solution, then using single photon counting technique to measure the photon number of records the concentration of analytes. Mechanical parts of the system including the measuring chamber, photomultiplier tubes, reagent storage, reagent pumps;electronic system including electronic systems for motors, pumps, valves and other components to control power,photon counting, LCD display and key modules, printers modules. the sensitivity of the test to meet the technical requirements.
Keywords/Search Tags:Immunodiagnostic, Chemiluminescence, Single photon counting
PDF Full Text Request
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