With Copd With Acute Exacerbation Of Tcm Syndrome And Airway Responsiveness In The Relationship Between

Retrospective reviewing through 130 cases of acute exacerbation of chronic obstructive pulmonary disease (AECOPD), by patients'age, gender, course of disease, morbidity cause, smoking history and other regular conditions. Further study and analysis on patients' symptoms, pulse, tongue, WBC counts and lung functions. Discuss on airway responsiveness in different AECOPD TCM syndromes and the relationship with other related factors. This study purpose is to find out the objective TCM diagnoses pattern on COPD by analysis the correlation between airway responsiveness in different AECOPD TCM syndromes and the course of disease.Results:①Elder COPD patients are easily effect by exogenous factors which aggravate the condition (P<0.05), and also worsen the lung function (P<0.05);②Smoking exacerbate COPD patients'FEVi/FVC%;③Lung function improvement rates are higher in non-exogenous factor effect patients;④Patients with longer course on illness are more easy to effect by exogenous factors and turn into acute exacerbation phase (P<0.05);⑤Patients with asthma have bad lung functions, while they have better response to bronchodilator (P<0.05) then those without asthma complication;⑥The course of AECOPD have intrinsic connection with TCM syndromes, pattern orders as:Exterior cold with interior phlegm→Phlegm obstructing the lung→Phlegm-heat obstructing the lung→Lung and kidney Qi deficiency, phlegm stasis in lung (P<0.05);⑦Different patterns of TCM syndromes as lung function decline:Exterior cold with interior phlegm→Phlegm-heat obstructing the lung→Phlegm obstructing the lung→Lung and kidney Qi deficiency, phlegm stasis in lung (P<0.05);⑧There are significant statistic difference in airway responsiveness between "Exterior cold and interior phlegm" and "Lung and kidney Qi deficiency, phlegm stasis in lung" syndrome AECOPD patients (P<0.05).Conclusion:The process of TCM syndromes of AECOPD are from excess to deficiency, regular pattern:Exterior cold and interior phlegm→Phlegm obstructing the lung→Phlegm-heat obstructing the lung→Lung and kidney Qi deficiency, phlegm stasis in lung. Pertaining to lung function and TCM syndromes:Exterior cold with interior phlegm→Phlegm-heat obstructing the lung→Phlegm obstructing the lung→Lung and kidney Qi deficiency, phlegm stasis in lung. Smoking exacerbate COPD patients' FEV1/FVC% There are significant statistic difference in airway responsiveness between "Exterior cold and interior phlegm" and "Lung and kidney Qi deficiency, phlegm stasis in lung" syndrome AECOPD patients. This study shows that there are intrinsic connections among different AECOPD syndromes and related indicators, and provide an objective guideline in TCM syndrome diagnosis for AECOPD.