Generally,for curing fever,inflammation and so on,many antibiotics have been used.But continually taking these antibiotics may bring drug resistance to the patient,even endanger the patient.Comparatively,Traditional Chinese Medicine doesn't have such side effect.Artemisia annul,which grows in the whole nation,is often used for curing such diseases as icterus,ague and fever. Specially,Artemisinin which is distilled from Artemisia annva has been widely used for curing ague and has great curative effect.These years,the research about Herba Artemisiae annuae oil has been carrying on gradually,and it has been manifested by pharmacological research that Herba Artemisiae annvae oil has the function of antivirus,antifebrile and antipyretic,and has good effect even using few dosage.Herba Artemisiae annuae oil has the great prospect to be used on clinical.Studied the chemical composition of Herba Artemisiae annuae oil by GC-MS, and obtained the composition of chemical components.As certained the index component and its controllable preparation technics,and studied the identification of chemical conformation.Based on these studies,establish the method to determinate content of index component and the base for after study of pharmaceutics.On the study of preparation of Herba Artemisiae annvae oil and Herba Artemisiae annuae oil soft capsule,firstly,researched the methods of extracting,the conditions of extracting,the methods of purification and the conditions of purification.According to the results of extracting and purification,the crafts had been decided.Secondly,paid more attention on the preparation craft of Herba Artemisiae annuae oil soft capsule.At last,to prove the preparation methods was suitable for commercial process.On the study of quality standard of Herba Artemisiae annuae oil and Herba Artemisiae annuae oil soft capsule,contained characters, examination,determination of content.After that,the stability of Herba Artemisiae annuae oil and its soft capsule were detected.The results proved they had good stability.The innovations are the study of Herba Artemisiae annuae oil components deeply;and the establishment of the method for determining the content,which is sensitive,accurate,and has good repeatability,at the same time,useful for the quality control of others drugs containing Herba Artemisiae annuae oil, what's more,the successful development of the soft capsule dosage form of Herba Artemisiae annuae oil takes great convenient to the patient and enriches the market of Chinese formulated products. |