Integrative Comprehensive Treatment Program On The Clinical Efficacy Of Pulmonary Heart Disease With Acute Exacerbation Of Observation

Objective:To value the curative effect of the combination treatment project of Chinese and Western Medicine during the acute attack stage period of chronic pulmonary heart disease (CPHD) by a randomized controlled, single-blined, paralleled clinical trial. Try to study the optimized remedial project to adapt the China situation during the acute attack stage period of pulmonary heart disease.Methods:1. Reviewing TCM ancient works about CPHD and summarizing the TCM achievements of the CPHD in the latest twenty years.2. Generalizing the resarches progresses of the diagnosis, treatment and prevention of CPHD.3. With prospective, randomized, single-blined, paralleled controlled trial, 80 patients with acute attack stage period of CPHD were randomized divided in two groups. One is the control group and the other is the cure group. The patients in the cure group were treated with combination treatment project of Chinese and western medicine. Therapeutic methods are following:dispersing the Lung to relieve asthma, resolving phlegm and checking cough. Prescriptions used are San Ao Decoction, Gua Luo Xie Bai Ban Xia Decoction and Jie Geng Decoction. Modification:For patients with Lung and Spleen deficienc, Xiang Sha Liu Jun Zi Decoction was added to strengthen the Spleen and nourish the Lung. For patients with edema due to Yang deficiency, Ling Gui Shu Gan Decoction was added to warm Yang and induce diuresis. The patients in the control group were treated with Western therapy. All the patients were cured for 14 days. Indexes evaluated were following: effect indexes (the whole effect, integra of main and secondary symptoms in TCM, signs integra in modern medicine, arterial blood gas analysis, personal living ability evaluation and so on).Results:No significant differences among two groups with 14 days fatality rate. It seemed that the cure group has the better curative effect, the symptom, and the sign etc, increasing partial pressure of arterial blood Oxygen pressure than those of control group.Conclusions:1. The CPHD is one of the diseases of Western medicine, but the TCM ancient books and records about CPHD were abundant and detailed which was worth inheriting. Though a great deal of progresses of CPHD were achieved by the modern TCM doctors, more research was needed in the integrated Traditional Chinese and Western Medicine treatment program on the acute stage period of CPHD.2.The elemental research indicates the combination treatment project of Traditional Chinese and Western Medicine has probably advantages in increasing the whole effect, improvement of symptoms,signs,pulmonary function and personal living ability. The research supply beneficial references in studying the optimized prevention and remedial project to adapt the China situation during the acute attack stage period of pulmonary heart disease.