Ea Quchi Xue Blood Pressure And Hypertension Rat Model Of Tumor Necrosis Factor, Nitric Oxide In

Objective:Hypertension (EH) is characterized by arterial hypertension, and later accompanied blood vessels,brain,heart andkidney disease and multiple common diseases. The prevalence rate is as high as 10% to 20%, is seriously endangering the health of the major diseases of mankind. Over the past 20 years the incidence of hypertension in China has almost doubled, from hypertension caused by cardiovascular disease mortality has been into the all of a disease mortality. Hypertension serious damage to people's health and life, it is not only an independent disease, at the same time as cardio-cerebralvascular disease risk factor, resulting in heart,brain,kidney,blood vessels,the structure and function of thefundus changes and damage, cause-related diseases. Prompt diagnosis and standardized control of hypertension has become a global medical profession an important research topic.Acupuncture is a part of Chinese traditional medicine, is a more effective treatment. In recent years, the majority of medical workers in treating hypertension acupuncture Clinical and Experimental Research has done a lot of work, not only affirmed the acupuncture treatment hypertension good effect ,and found that the mechanism of acupuncture buck are many,many levels, Multi-link adjustment role. However, thesestudies from the time of onset are not unified, acupuncture inconsistent approaches, the selection of acupuncture points are totally different to the evaluation of difficulties. Therefore,the study of single-point buck to study the effect of acupoint must become law. By observing this topic electro acupuncture Quchejue hypertensive rats, observe its antihy pertensive effect, and in order to thoroughly explore the immune mechanism of acupuncture relief, the subject observed acupuncture Qu Chi pionts hypertensive rat model of serum tumor necrosis factor (TNF-α) and nitric oxide (NO) / nitric oxide synthase .(NOS) in the impact from the perspective of pathophy siology buck acupuncture provide a theoretical basis, with a view to specific acupuncture point theory to provide a scientific basis for the Clinical Acupuncture Points provide experimental basis for the election.Methods:Healthy adult rats SD 50, male and female Geban, according to the principle of randomized, the normal group (10), the sham group (10), the model (30). Four weeks after the model, the model identification, will form a stable hypertensive ratswere randomly divided into control group (10只) , electroacupuncture group (10只) . The kidney used to establish a folderof the hypertensive rats (2 K1C-RHR) model, the animal model. Electro-acupuncture group from Qu Chi points, RIA detection of serum TNF-α, enzymatic detection NO / NOS content.Results:1. The normal control group and the sham group of blood pressure and serum TNF-α, NO/ NOS in no significant difference (P> 0.05).2. Model group and the control group, the sham group, high blood pressure, levels of TNF-αwas increased, NO / NOS in lower, with a very significant difference (P <0.01). 3. Electro-acupuncture group, as group after treatment for blood pressure drop of serum TNF-αin the lower, NO/NOS content increased, electro-acupuncture group compared with the model group a very significant difference (P<0.01).Conclusion:1. EA Qu Chi pionts a certain antihypertensive effect.2. Electroacupuncture Qu Chi points model of hypertension in serum TNF-αand NO/NOS in a certain regulatory role.3. Qu Chi pionts electro-acupuncture can reduce TNF-αand increased NO, NOS content. Acupuncture is one of the mechanisms of relief could be adopted to reduce inflammation, regulating blood vessel contraction to achieve.