Rhubarb, Licorice Soup Side To Retain The Enema Of The Efficacy Of The Treatment Of Sirs In Patients With Gastrointestinal Dysfunction Observed

Destination: Through this investigation to approach and to uncover the utility therapeutic tools about Tradition Chinese Medicine(TCM) for the SIRS patients that have been to trouble the stomach intestine dysfunction, and to confirm the huge value about TCM to cure emergency and severe case.Process: According to the ran and contrast control principle, to bring the patients(60) into the management-group(MG) and control group(CG) one by one, each group has 30 patients, they all will be treated on the routine method, but the MG patients will be given the retention-enema RX used medicinal broth named Rhei and Glycyrhizae Decoction Series, course of treatment is 3 days; draw blood before the treatment and after it, conserve the specimens, detected the quantitation of MTL(motilin) and VIP(vasoactive intestinal peptide) by radio-immunity(RI) to observe the impacts from the TCM, moreover, made a comparison on the scores of the stomach intestine dysfunction(prior treatment and post-treatment), then it will be confirmed that TCM is effective.Consequence:1 Observation of the common condition(1) Clinical symptom:Both the management-group and the control group felt better after treatments than before, especially abdominal distention has been lessened, but the management-group had a larger effective power, the comparison had a predominant statistics difference(P<0．01) ,and the management-group patients had more egestion times(P<0．05) .(2) Physical sign: After treatments, register the times of bowel sound, both two groups' had increased (P<0．01) ,but the figure of the management-group was larger than the control group's, the comparison had a predominant statistics difference(P<0．05) .Furthermore, to make an effective power judgment about the total patients, the management-group was higher than the control group (P<0．05) .2 The scores of the stomach intestine dysfunctionCompared with the prior treatment, the scores of two groups decreased obviously after treatment (P<0．01) , and the management-group was higher(P<0．01) ,but two groups had no significant difference (P>0．05) in the prior treatment.3 The evaluation of curative effect about the clinical symptom and the physical sign3．1 The comparison on the times of bowel soundBoth groups were increased after treatment (P<0．01) ,compared with the control group, the times of the management-group was more (P<0．05) , but two groups' had no significant difference (P>0．05) in the prior treatment.3．2 The comparison on the times of the patients' egestionTo do a nonparameter test about the times of two sets , the result displayed : Z:-2．053, P=0．040, P<0．05, and the mean ranks of the management-group was higher.3．3 The comparison on the amelioration of abdominal distentionResult display: Compared with the control group, the effective power of the management-group was higher (P<0．01) .4．The comparison about the contents of human plasma MTL and VIP4．1 The contents of human plasma MTL of Two sets had an obvious increase after treatment (P<0．01) , compared with the control group, the increase of the MTL contents in the management-group was more (P<0．05) , but two groups' had no significant difference (P>0．05) in the prior treatment.4．2 The contents of human plasma VIP of Two sets had an obvious decrease after treatment (P<0．01) , but two groups' had no significant difference (P>0．05) in the prior treatment and after treatment(P>0．05) .5．The dependablity analysis between the contents of human plasma VIP/MTL and the scores of the stomach intestine dysfunction.5．1 The regression equation about the contents of human plasma MTL (x₁) and the scores of the stomach intestine dysfunction (y₁) was: y₁=-0．002x₁+2．098, R=0．537, P<0．01, it means that the relationship within the contents of human plasma MTL and the scores of the stomach intestine dysfunction was negative correlation.5．2 The regression equation about the contents of human plasma VIP(x₂) and the scores of the stomach intestine dysfunction (y₂) was: y₂ = 0．018x₂, R =0．888, P<0．01, it means that the relationship within the contents of human plasma VIP and the scores of the stomach intestine dysfunction was positive correlation. Conclusion:The curative effect of treating SIRS patients that have the stomach intestine dysfunction by retention enema of series Rhei and Glycyrhizae Decoction is certain, have no manifest adverse effect; can relieve clinical symptom(abdominal distention, costiveness), and improve the score of stomach intestine function. The mechanism is increasing the motivation of stomach intestine and defending the intestinal tract mucosal barrier through increasing MTL and decreasing VIP, preventing breed of pathogenic bacterium and development of pyaemia, improving patients' nutritional state, forbidding the stomach intestine dysfunction to develop the MODS at the starting point, improving the achievement ratio of salvaging heavy patients.