Platanus Acerifolia Pollen Is The Main Change To The Original Coding Gene Cloning And Expression

Background Over the past few decades, the incidence of various allergic diseases are markedly increasing in worldwide range, especially in the industrialized developed countries, allergic diseases seriously depress the quality of life for residents, enhance medical expenses, resulting in economic losses, and has become a global health problem. About one fifth of population belongs to atopic constitution and easy to suffer from allergic diseases. The World Health Organization has placed such diseases as the diseases that should be regarded with intensified research and prevention in the 21 century. Pollen is one of the most common aeroallergen which may induce many kind of allergic diseases such as rhinitis, bronchial asthma, allergic conjunctivitis. Pollinosis is so-called seasonal allergic rhinitis or hay fever, Platanus acerifolia pollen is found as an allergen which induces hypersensitive reaction in the atopic subjects in the southern region of China with arising incidence. The research on its constitution of antigenic epitopes and characteristics of molecular biology are beginning to be recognized by researchers during the recent years.The artificially recombinant allergen produced by genetic engineering provided inimitable advantages compared to the extraction of natural allergens and the recombinant protein of common allergens incomparable advantages abroad has already begun developing a common change to the original manual of protein, and gradually applied to the clinical diagnosis and specific immune...