| Several herbal medicines compose formula, which is basic form in the treatment of Traditional Chinese Medicine. The compatibility of medicines is variable, however it also has its special rules. In this article we focus on the "medicine pair" which is one of the compatibility forms of formula, and try to discover the skills and rules of compatibility of two medicines among pieces of formula".This article take 1046 pieces of formula as sample, and deal with the information of medicine and formula by the method of data processing, then to analysis and discover the application and compatibility rules of "medicine pair" among pieces of formula by Knowledge Discovery in Database (KDD). The content of this research mainly include:First, data preparation of medicine and formula. According to the regulations of sample collecting, we select formula in treating spleen and stomach from "Dictionary of TCM--Formula" which is one of the most authoritative reference book of formula, and deal with the information of medicines, symptoms, function and dosage etc., by the method of standardizing, datamation and transformation, and then obtain science data.Second, construction of database for formula and syndrome. After data processing we input information into Access Database, which include database of formula, database of symptoms and database of medicines. Moreover, we build up repository database to store the basic information and rules of prescription, which are often used in the process of data analyzing and knowledge discovering.Third, data mining for compatibility rules of "medicine pair". Data analysis is done on the "medicine pair" among spleen and stomach formula by KDD, such as Association Rules, Clustering Analysis and Data Classification etc., the content of the analysis include nature and flavor analysis, dosage analysis, function analysis and symptom character analysis of "medicine pair".This article focus on the "medicine pair" and carry out the research based on effective formula, and to explore the relationships between "medicine pair" and corresponding factors in prescription. This research proofs that the method of KDD can be used to recognize the compatibility rules of "medicine pair" in formula, and discover the law among them, which has great significance for deep research of compatibility of formula, optimizing prescription and improving curative effect. |