| Radix Polygalae is the root peels of a Polygala tenuifolia family perennial herb Polygala tenuifolia Wild or ovum leaf Polygala sibirica.It can benefit intelligence and calm the nerves , eliminate the phlegm for diminishing swelling. On clinic, It is used in disharmony of Heart and Kidney,insomnia and dreaminess,amnesia and palpitation etc. The herb starts to be stated from Shen Nong Ben Cao Jing. As one of the traditional medicines in China, Its clinical practice is quite extensive.Though nonpoisonous in the herbal history, The clinical practice is raw and processed Yuanzhi.The processing methods of Radix Polygalae have certain historical evolution too.According to the records of document,there are more than 10 kinds ( processing methods). At present,we usually use Gancao-zhi Mi-zhi Jiang-zhi etc. Traditionlly we think Sheng YuanZhi have side effect of throat, it can cause intestines and stomach react such as nausea and vomitting etc, so often for external use, To take orally,we often use processed crude herbs. On clinic ,the side effects of Radix Polygalae lie in intestines and stomach react . In order to make Radix Polygalae reduce malicious function and enlarge to investigate mainly, define its pharmacology function further , we have done many experiments,the contents are as follows: LD50 of Sheng YuanZhi Mi YuanZhi Zhi YuanZhi and Jiang YuanZhi, the acute toxic experiment of intestines and stomach, the impact on the intestines and stomach move and digestive function paroxymal cough eliminating the phlegm tranquillizing lulling and improving study and memory etc. The result shows : LD50 of Sheng YuanZhi is smaller than other products , the inhibition that the intestines and stomach move of Sheng YuanZhi is greater than the products . The relevant pharmacological action indicate: As to Sheng YuanZhi Mi YuanZhi Zhi YuanZhi and Jiang YuanZhi, they have veryremarkable functions that lie in paroxymal cough and eliminating the phlegm , but Mi YuanZhi's benefiting intelligence and calming the nerves function is stronger than Sheng YuanZhi and other products. As a whole, yuanzhi processed can reduce malicious function and enlarge efficacy, This accords with the theory that processing can reduce herb 's toxicity and side effects, So clinically propose that it is good with Mi YuanZhi... |