| Objective:The incidence of alcoholic liver disease increased year by year to becomethe second largest after the viral liver disease. Studies have shown that alcoholic liver fibrosis stage of a reasonable and timely treatment can be reversed and Chinese medicine in the alcoholic liver fibrosis preventive and therapeutic areas reflect its obvious advantages. This study on alcoholic liver fibrosis syndrome classificationstudy, also related to its distribution of TCM clinical syndrome, Syndrome Distributionand characteristics of distribution of pattern elements and the associated risk factorsand related physical and chemical inspection and distribution Syndrome To study the correlation between the same time, combined with alcohol liver fibrosis with HBV infection and alcohol drinking to clear due to different causes of liver fibrosis in patients withsyndrome characteristics, syndrome and syndrome factors for the distribution ofexploratory research. At the same time to further improve results also lay the foundation for clinical efficacy.Methods:The thesis is divided into two parts, the first part, theoretical. The second part, the clinical research component. Through the first part of the four aspects. First, the preliminary summary of the alcoholic liver fibrosis in chronic Hepatitis B and alcohol in medicine related to its understanding; Secondly, summed up the non-invasive diagnosis of liver fibrosis progress; third, summed up the TCM Syndrome Research progress; fourth, summed up the essence of the Card element in the study of liver fibrosis research progress. The second part, clinical research component, through the multi-center, prospective study of patients with alcoholic liver fibrosis in clinical data collection, collected from Shandong and Beijing and many other hospitals of the 115 cases Cases of alcoholic hepatic fibrosis, and 85 cases of chronic hepatitis B patients with hepatic fibrosis combined alcohol and requested the establishment of case related data entry database statisticians, take the second entry by entry of different, and the principal component factor analysis, Logistic regression analysis Statistical methods, epidemiology, the frequency distribution of syndromes, analysis of disease syndromes related indicators and statistical correlation.Result:The mainly Risk Factor of ALF and HBV infection and alcohol drinking is Smoking and alcohol for a long time consumption. It conclusion that Spleen Deficiency syndrome (39.13%)> Retention of Damp-Heat syndrome (28.70%)> Deficiency syndrome of both liver and kidney yin (9.57%)> Qi and yin Deficiency (8.70%)) Obstruction of Collaterals by blood stasis syndrome (7.83%)> Spleen and kidney Deficiency (6.09%). HBV infection and alcohol drinking conclusion that Retention of Damp-Heat syndrome (40.00%)) Spleen Deficiency syndrome (27.06%)) Obstruction of Collaterals by blood stasis syndrome (11.76%)> Deficiency syndrome of both liver and kidney yin (10.59%) and Qi and yin Deficiency (10.59%) Physical examination results on the statistics:GGT, PT, IV collagen and alcoholic liverfibrosis syndrome distribution was statistically significant, I hope the above article onthe physical and chemical alcoholic liver fibrosis check between the syndrome distribution Relations, can be introduced alcoholic liver fibrosis syndrome area.Conclusions and research characteristics:First, the conclusion:the length of time in patients with alcohol and smoking has a chronic alcoholic liver fibrosis and alcoholic liver disease Hepatitis B common risk factors, so in the clinical treatment tell patients drinking should also quit smoking. Second, the main features of this study are as follows:Through the collation of data and statistics, the initial establishment of alcoholic liver fibrosis and fibrosis in chronic hepatitis B combined factor analysis model for alcohol and alcoholic liver were revealed fibrosis and HBV infection and alcohol drinking of TCM syndromes, the alcoholic liver fibrosis standardization of TCM, while enriching the classification of syndromes. The relevant physical and chemical examination of the introduction of TCM syndrome of alcoholic liver area of the fiber. |