Patients With Acute Coronary Syndrome Risk Stratification Of Coronary Lesions Relevance Of Clinical Research

Background:Acute coronary syndrome ( ACS ) is a clinical syndrome which caused by the instability and vuluerability of plaque , and in which there are three clinical types : unstable angina ( UA ) ,no-ST segment elevation myocardial infarction ( NSTEMI ) and ST segment elevation myocardial infarction ( STEMI ). In recent years, the first two together in turn called non-ST segment elevation ACS (NSTEACS) , which is known as ST-segment elevation ACS (STEACS). ACS patients with short and long term prognosis of a greater difference, so the correct identification of high risk ACS and to give timely and effective treatment can significantly improve on the outcome. Evaluation of the current international level on a variety of risk stratification in patients with ACS method, which GRACE and TIMI risk stratification risk classification system is the most widely used risk stratification. Coronary angiography is the current diagnosis and clinical treatment of coronary heart disease the "gold standard." Clear risk stratification of ACS and severity of coronary artery disease correlated to guide physicians in the acute phase of diagnosis and treatment of patients, for patients to better themselves and their families choose and effective treatmentstrategies, and provide a more rational allocation of clinical resources Adequate theoretical basis. At home and abroad for the risk stratification of ACS focused on risk stratification of patients with short and long term adverse cardiovascular event probability forecasts and the forecast to determine the degree of coronary stenosis, etc, but the correlation for the two Less study. Purposes:Clear risk stratification of ACS and the related coronary artery stenosis and its effect on the predictive value of disease development, so as to provide a theoretical basis for the treatment of ACS.Methods and Results:Select April 2010 to December 2010 admitted to hospital and diagnosed as ACS with complete data were 215 cases, including non-ST-segment elevation ACS patients with 160 patients, ST-segment elevation ACS patients with 55 cases. For each patient, GRACE and TIMI risk stratifications were calculated by using specific variables collected at admission. Patients were classified into 3 categories (low, middle and high risk) according to GRACE and TIMI risk stratifications. The results of coronary angiography in every patient were also reviewed. The relationships between ACS risk stratification and extent or severity of coronary artery stenosis were analyzed. One-vessel lesion and mild stenosis of coronary artery were more often found in patients with low risk group by ACS risk stratifications, and three-vessel or left-main lesions and heavy stenosis of coronary artery were more often found in patients with high risk group by ACS risk stratification.Conclusion:ACS risk stratification methods and extent of coronary arterystenosis correlation, the degree of coronary artery disease in patients with higher clinical predictive value.