A Systematic Evaluation Of Traditional Chinese Medicine (tcm) In Treating The Psoriasis

[The Background]Psoriasis is a chronic recurrent inflammatory dermatosis. It occurs young people and often recurrent that often requires lifelong treatment and have great effects on body and psyche. Psoriasis may express as a few coin-sized erythematosquamous plaques up to widespread. It has a long history for the Traditional Chinese Medicine (TCM) to treat the psoriasis and accumulates a great deal of clinical experience. Combing traditional Chinese and western medicine can shorten the curative period and alleviate the side effect which has been invoked by the pure western medicine. But we can not evaluate the validity and security systemically of the psoriasis treated by TCM or Combined Traditional Chinese and Western Medicine. So we do it.[objective]To know the literature situation on the psoriasis treated by TCM and Combined Traditional Chinese and Western Medicine, to evaluate the validity and security systemically of the psoriasis treated by TCM or Combined Traditional Chinese and Western Medicine.[Method][The first:The evaluation of literature designate quality the psoriasis treated by TCM.]To collect the clinical reference study literature published from 1986-12.2006. According to the inclusion criteria of literature and include clinical epidemiology/D.M. E's principle and methods, we designed the unitive systematic review table of the treatment on psoriasis by TCM and Combined Traditional Chinese and Western Medicine to evaluation of Controlled Clinical Trial literature designate quality the psoriasis treated by TCM. On the basis of the inclusion criteria or exclusion criteria, reference situation, sample size, the group balance, the use of the control drugs, random situation, blind method, the method of the statistics, standardization of the control factors, curative judgment index, the analysis of the drop out or lost, the record or analysis of the side the percentage of all effect, the rationality of the conclusion, we compute kinds of situation and do a evaluation.[The second:The Meta Analysis on the psoriasis treated by TCM]To collect the clinical reference study literature published from 1986-12.2006. According to the inclusion criteria of literature, we use the Revman 4.2.8 software, we do the meta analysis, sensibility of the different design sensibility analysis between the random factor and fix factor model, then we draw the funnel plot and analyze the bias on the publication. [results and Conclusion]1. The quality-Analysis result of study of literature indicate that there are respect table problem in the Controlled Clinical Trial literature reports on the psoriasis treated by TCM and Combined Traditional Chinese and Western Medicine. The primary manifest are that random situation,blind method,ample size,the group balance,the method of the statistics。2. Meta_ Analysis result indicate that TCM or Combined Traditional Chinese and Western Medicine do really have the good therapeutic efficacy on the psoriasis, the result is better than qindai pills/capsules, than diyin tablet. Sensibility of the different design sensibility analysis between the random factor and fix factor model, we do the same conclusion.