Analysis On The Pathogens Of 72 Cases Of Community-acquired Pneumonia And Drug Resistance Of Isolated Bacte

Objective To investigate the pathogens of community-acquired pneumonia ( CAP) , and study the drug resistance of isolated bacteria.Method A prospective study was performed on 72 adult patients with CAP from 2008. Sputum samples were collected for culture. Bacteria were isolated and identified using conventional methods and their Minimum Inhibitory Concentration (MIC) were determined. Antibodies of the paired serum samples to Mycoplasma pneumonia, Chlamydia pneumonia, and Legionella pneumophila were detected.Results The etiology of CAP was identified in 21 patients(26.25%). Among the patients , Streptococcus pneumoniae 10, Haemophilus influenzae 8, Klebsiella pneumoniae 3 bacillus pyocyaneus w as 2, Staphylococcus aureuswas 1, , Mycoplasma pneumonia 6,Chlamydia pneumoniae 4,. Legionella pneumonia was 1,mixed infection were 8,The non-susceptibility rates of Streptococcus pneumoniae to penicilin and azithromycin were 70.00% and 80% , The drug resistance rate of Haemophilus influenzae to ampicillin was 62.50%.Conclusion Streptococcus pneumoniae and Conclusion Haemophilus influenzae were the most common bacteria for CAP. Adult CAP was caused by atypical pathogens (Mycoplasma pneumonia) and the rate of mixed infection was high. The drug resistance rate of Streptococcus pneumoniae to penicilin and azithromycin was high. The use of antibiotic shoud base on the epidemiology of infectious disease and the treatment of CAP patients should cove atypical pathogens.