Analysis Of TCM Syndromes Of Primary And Middle Liver Cancer

Objective:This study aims at discovering the TCM syndromes distribution characterist-cs of primary hepatic carcinoma(PHC),analyzing the relationship between different TCM syndromes of PHC patients and the laboratorial indexes AFP and liver function by systemat-ically analyzing complete medical records of patients with PHC.This study tries to provide reference of TCM syndromes classification and better guidance to the clinical diagnosis and treatment of PHC.Method:In this study, a retrospective clinical case study method was used to establish a unified information collection form for patients with PHC. According to the inclusion criteria and exclusion criteria, the clinical data of 118 patients with PHC were collected,who were admitted to the Yuelu District people’s Hospital in the city of Changsha of Hunan ProvinceProvince. According to the standard of TCM differentiation type, the TCM sydrome of patients were assessed. We used the original data to statistically describing and analyzing.Results: ①The 10 major clinical symptoms of PHC patients were as follows:hypochon-drium pain (77.12%), loss of appetite and eat less (71.19%), abdominal distension (50.85%), fatigue (50.00%), lump in the abdomen (38.98%), bitter taste of mouth (27.12%), dry mouth (26.27%), dark complexion (22.03%), loss of sleep (19.49%), stool discharge (19.49%).②The most occurrence of singleTCM syndrome of PHC patients was spleen deficiency syndrome with 71times(60.17%), the rest of the syndrome from high to low were as follows: Qi stagnation is 50 times (42.37%),blood stasis syndrome was 32 times(27.12%), syndrome of dampness heat syndrome for 30 times (25.42%), yin deficiency syndrome for 30 times (25.42%). These single TCM syndromes were often combined together to form a composite TCM syndrome in the clinical treatment of PHC.③There were only 34 patients with single TCM syndrome, accounting for 28.81%, while 84 cases were composite TCM syndrome, accounting for 71.19%. The occurrence of composite TCM syndrome from hige to low were qi stagnation and spleen deficiency syndrome with 28 cases (23.73%),11 cases of spleen deficiency and blood stasis syndrome (9.32%),11 cases of yin deficiency of damp heat syndrome (9.32%) and deficiency of spleen yin deficiency syndrome in 9 cases (7.63%).④ There were no statistical significances of difference between AFP qualitative of different TCM Syndromes. The difference AFP levels of different TCM syndromes has statistically significance,which implicated AFP levels were different in different TCM syndrome.However, no correlation of TCM syndrome type and the level of AFP. were found in the Spearman rank correlation coefficient analysis.⑤ According to statistical analysis of the liver function indexes of PHC patients,there were disinct statistical significances of the serum levels of ALT, AST, TBIL between diffreent TCM syndrome. However, no correlation was found between TCM syndromes and liver function indexes in the Spearman rank correlation coefficient analysis.Conclusion: ① The most occurrence of single TCM syndrome of PHC patients was spleen deficiency syndrome, the rest of the syndrome from high to low were as follows:Qi stagnation,blood stasis syndrome, syndrome of dampness heat syndrome and yin deficiency syndrome. These single TCM syndromes were often combined together to form a composite TCM syndrome in the clinical treatment of PHC.The result suggests that the patients with PHC often take spleen deficiency syndrome as the present and we should pay attention to the use of the method of strengthening the spleen in the clinical treatment.The occurrence of composite TCM syndrome from hige to low were qi stagnation and spleen deficiency syndrome, spleen deficiency and blood stasis syndrome, yin deficiency of damp heat syndrome and deficiency of spleen yin deficiency syndrome. The study result suggests that the deficient root and excessive branch syndrome were frequent in the clinic of PHC patients.The clinical doctors should control the balance of banking up the root and getting rid of excessive branch in clinical intervention by traditional Chinese medicine.②There wrer no correlation between TCM syndrome type and the level of AFP and liver function indexes.However,the difference of AFP levels and liver function indexes in different TCM syndromes has statistically significance.We consider that the negative result were related to the small sample size and the conditional statistical method, and further research with larger sample and advanced statistical methods is needed to find out more significant research results to clinic.