| Background Primary Hepatic Carcinoma(referred to as PHC) is a high incidence of tumors of the common one, in the third highest ranking cancer [1], ranking fifth in the global incidence of cancer. Primary Hepatic Carcinoma of The pathogenesis is in the liver, under the Chinese " abdominal mass, " "jaundice, " " tympanites, " " costalgia "and other areas. More obvious early symptoms and signs, the majority of patients, advanced stage fatigue, anorexia, weight loss and other symptoms of treatment, then the rapid progression, death rate [1]. Each year about 11 million people died of liver cancer, the incidence of the number increasing every year. Therefore, early diagnosis of the disease and timely therapy, to improve the survival rate of patients with far-reaching.Objective This project aims to color Doppler ultrasound technique was different TCM syndrome types of primary liver cancer lesions and richness of color flow around the hepatic artery and portal vein blood flow parameters to understand the time of PHC hemodynamics, comparative analysis of the syndrome PHC Chinese characteristics and achieve with color Doppler ultrasound diagnosis in the noninvasive diagnosis of PHC to the early course of the disease, symptoms of Chinese medicine to provide objective quantitative indicators. Evaluation of primary liver cancer syndromes and color Doppler ultrasound characteristics of the relationship between, for the TCM clinic to make an accurate diagnosis of early hepatocellular carcinoma and selection of appropriate treatment programs provide an objective basis.Methods 90 patients with biopsy proven primary liver cancer patients, according to inclusion criteria and exclusion criteria selected as case group, according to People's Health Press,2006, "Chinese medical science" will be trapped in case group is divided into Spleen wet-type, gas stagnation and blood stasis type, heat poly drug type, liver-kidney IV. Another 50 cases of physical examination were selected as control group. In all cases two-dimensional, color Doppler, pulsed Doppler ultrasound to observe the contrast of different syndromes and two-dimensional sonographic features of lesions in and around the blood flow characteristics, rich in the tumor blood flow distribution by level level; and measure the maximum hepatic artery blood flow velocity (Vmax), resistance index (RI), pulsatility index PI; portal vein diameter (D), blood flow per minute (Q), mean flow velocity (TAMX) and other key blood parameters; to compare the above parameters, of different syndromes in patients with primary liver hemodynamic changes and the relationship between PHC lesions. Establish a database for statistical analysis using SPSS16.0 software, using descriptive analysis, class rank sum test was used to compare data; measurement data using analysis of variance, the variance by rank test were missing, two-sided test, a=0.05.Results1, the syndrome in and around the tumor between the richness of color flow display rate of a certain relevance, spleen deficiency with dampness retention MMS numbers show low blood type, and the other three types, the difference was statistically significant (P <0.05). The most abundant color flow display together for the heat poly drug type, and spleen deficiency with dampness retention and liver-kidney, the difference was statistically significant (P <0.05).2, portal vein blood flow per minute with blood stasis type of Q most significant increase, together with the control group and the heat toxin type, liver-kidney, the difference was significant (P <0.01). Portal vein diameter D widened to the most significant heat accumulation type virus, with the control group and the spleen deficiency with dampness retention, the difference was statistically significant (P<0.05). 3, the maximum systolic velocity in the hepatic artery, heat poly drug type drugs compared with control group, the difference was statistically significant (P<0.01). RI resistance index, heat poly drug type drugs compared with control group, the difference was statistically significant (P<0.05). Maximum velocity of systolic arterial liver-kidney compared with the control group, the difference was statistically significant (P<0.05). Resistive index RI liver-kidney compared with the control group, the difference was statistically significant (P<0.05).Conclusion Color Doppler ultrasound can be more accurate than the two-dimensional ultrasound diagnosis of PHC, not only non-invasive and intuitive display of the tumor characteristics of the syndrome, and can be different syndromes of Chinese medicine analysis and comparison of hemodynamics, more scientific symptom of Chinese medicine provides an objective quantitative indicators, color Doppler ultrasound in clinical diagnosis should be with the traditional Chinese combination of all the organic combination to achieve the complementary advantages. |
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