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Characteristics Of TCM Syndromes In Patients With Pulmonary Interstitial Fibrosis And Its Correlation With HRCT

Posted on:2017-01-04Degree:MasterType:Thesis
Country:ChinaCandidate:H H QinFull Text:PDF
GTID:2174330482484521Subject:Internal medicine of traditional Chinese medicine
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Objective:In order to explore the Traditional Chinese Medicine syndrome of pulmonary fibrosis characteristics and correlation with chest CT scan,our study collects and analyzes the clinical data of 74 patients with interstitial pulmonary fibrosis.And hopes that our study can provide a new thinking about treatment.Method:Our study records the basic informations and chest CT scans through the way of questionnaire to collect into 74 cases who meet the standard of pulmonary fibrosis.Analyzes the basic statistics using SPSS software,and summarizes the TCM syndrome charasteristics of pulmonary fibrosis and the correlation with chest CT scans.Results:(1)The age range of pulmonary fibrosis is from 55 to 92 years old,and the average age is 72.20±9.86 years old.The idiopathic pulmonary fibrosis and the secondary pulmonary fibrosis have the same distribution in different age classes and in men and women.The gender distribution is same in different age groups.(2)Chronic smoking and exposure of dust,poisonous and harmful gas are the important risks of pulmonary fibrosis. To some extent,pulmonary fibrosis are family inhertied diseases.(3)Pulmonary fibrosis are often with some chronic basic diseases, such as circulatory system diseases,respiratory system diseases and immune system diseases.(4)The common symptoms of pulmonary fibrosis are cough,sputum,shortness of breath,dyspnea.80% of the patients have cough.87.8% of the patients have sputum. The white color,thick,and the little sputum volume are in the majority.The severity of cough is not related with HRCT scores,and has the same distribution in the severity of HRCT. The sputum color and quality are not correlated with HRCT scores,and have the same distribution in the severity of HRCT.The sputum volume has moderate correlation with HRCT scores.85.1% of the patients are short of breath.The degree of shortness of breath is low correlated with HRCT scores.It has the same distribution in the severity of HRCT and the different age classes.79.7% of the patients have dyspnea.The severity of dyspnea has positive correlation with HRCT scores and the same distribution in the different age groups.(5)The main location of pulmonary fibrosis is lung.With the development of the disease,the location is lung and kidney.The spleen is involved at the same time. The idiopathic pulmonary fibrosis mainly locates in the lung,and the secondary pulmonary fibrosis mainly locates in the primary disease.The HRCT valves in the lung,kidney,spleen,heart,liver have no difference.The locations of lung,kidney,spleen,heart and liver have the same distribution in the degree of HRCT.The single,two,three,four and above locations have the same HRCT values and the same distribution in the degree of HRCT.(6)The character of pulmonary fibrosis is virtual real and standard of evidence,and it takes qi deficiency and yang deficiency as original cause,and blood stasis,cold phlegm and damp phlegm is the superficial cause. The basic nature is lung-kidney deficiency and phlegm and blood stasis syndrome. The HRCT scores of qi deficiency,xue deficiency,yin deficiency and yang deficiency are similar.The distribution of qi deficiency,xue deficiency,yin deficiency and yang deficiency in the HRCT degree are in the same.The sputum dampness,hot phlegm,dry phlegm,cold phlegm,wet resistance,hot,cold,qi stagnation,blood stasis have the same HRCT values,and the same distribution in the degree of HRCT.(7)Imaging features of pulmonary fibrosis are glass opacity,reticular shadow and honeycombing.91.9% of the patients have reticular shadow.The HRCT degrees include mild,moderate and severe.36 patients (48.6%) are in the mild HRCT degree,35 patients(47.3%) are in the moderate HRCT degree,3 patients(4.1%)are in the severe degree.The scores of TCM syndrome have moderate correlation with the HRCT values.The smoking and non-smoking patients have the same HRCT values, but have different distribution in HRCT degree.The idiopathic pulmonary fibrosis and the secondary pulmonary fibrosis have the same HRCT values,and have the same distribution in the HRCT degree.The MMRC dyspnea index have low correlation with the HRCT values.Conclusion:(1)The pulmonary fibrosis often happen in elder person,and have the same morbidity in men and women. The idiopathic pulmonary fibrosis and the secondary pulmonary fibrosis have the same distribution in different age classes and in men and women.The gender distribution is same in different age groups. Chronic smoking and exposure of dustjpoisonous and harmful gas are the important risks of pulmonary fibrosis. Pulmonary fibrosis are often with some chronic basic diseases,such as circulatory system diseases,respiratory system diseases and immune system diseases.(2)The common symptoms of pulmonary fibrosis are cough,sputum,shortness of breath,dyspnea. The main location of pulmonary fibrosis is lung. With the development of the disease,the location is lung and kidney.The spleen is involved at the same time. The idiopathic pulmonary fibrosis mainly locates in ht lung,and the secondary pulmonary fibrosis mainly locates in the primary disease. The character of pulmonary fibrosis is virtual real and standard of evidence,and it takes qi deficiency and yang deficiency as original cause,and blood stasis,cold phlegm and damp phlegm is the superficial cause.The basic nature is lung-kidney deficiency and phlegm and blood stasis syndrome.(3)The HRCT scores and the degree of HRCT can access the severity of pulmonary fibrosis.With the development of the disease,the HRCT scores become larger, and the degree of HRCT become severer.The scores of TCM syndrome are higher,the HRCT values are larger.
Keywords/Search Tags:pulmonary fibrosis, clinical trail, TCM syndrome
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