Clinical Research For Optimal Combination Of Acupuncture Treatment On Hypercholesterolemia

Hyperlipidemia is refers to the serum (or plasma) one or several lipid concentration significantly increased. While high blood is one of the reasons for causing cerebrovascular and heart disease. The part of the cholesterol rising is the most important factor of causing CHD, atherosclerosis. Etc. With the development of society, people's living standards improved at the same time, and the pressure from work or family increased. These are carrying the changes in the diet and lifestyles. Finally, resulting in the raising of the incidence of hyperlipidemia and making it much younger. People also gradually realize dyslipidemia is the important and independent risk factor of CHD. Therefore, how to prevent against the hyperlipidemia, especially the effective method of non-drugs, is a particularly important meaning in cerebrovascular disease. Now in the treatment of acupuncture and moxibustion in hyperlipidemia has a very good effect of adjusting lipid. But according to the relevant literature, there are very big differences during the uses of points, methods and period of treatment on the clinical application. So I choose the orthogonal experiment in order to explore the optimal combination of acupuncture treatment on hypercholesterolemia.Objective:By using different acupuncture methods, choosing different acupuncture points and different periods of treatment on treating hypercholesterolemia. Observing the magnitudes of total cholesterol (TC) before and after the treatment and comparing the clinical effect. Through summarizing the results to explore the optimal combination of acupuncture therapy hypercholesterolemia.Methods:According to "The Chinese herbal medicine clinical research guiding principles" for the treatment of hypercholesterolemia clinical research guiding principle. Choosing 3 factors and 3 levels of the orthogonal test design. The application of L9(34)orthogonal test table, using random distribution method to the patients with hypercholesterolemia as points of spleen, stomach and pericardial meridian+moxibustion+1 period of treatment; points of spleen, stomach and pericardial meridian+electro acupuncture+2 periods of treatment; points of spleen, stomach and pericardial meridian+point injection+3 periods of treatment; Back-shu points+moxibustion+2 periods of treatment; Back-shu points+electro acupuncture+3 periods of treatment; Back-shu points+point injection+1 period of treatment; points of Conception Vessel+moxibustion+3 periods of treatment, points of Conception Vessel+electro acupuncture+1 period of treatment; points of Conception Vessel+point injection+2 periods of treatment; and five patients each group, totaling 45 patients. During the treatment, patients can keep the original diet and lifestyles, not taking any drugs that can make influence to blood metabolism. Before and after treatment, they should draw blood for a test of TC.Results:Through the results of the orthogonal test:all groups could reduce the magnitude of TC. The optimal combination is the points of spleen, stomach and pericardial meridians+ moxibustion+3 periods of treatment(FC>FB>FA, KA1>KA3>KA2, KB1>KB3>KB2, KC3>KC2>KC1). All groups' symptoms of TCM are relieved after the treatment. But the optimal combination is points of Conception Vessel+moxibustion+3 periods of treatment (FC >FA>FB, KA3>KA1>KA2, KB1>KB2>KB3, KC3>KC2>KC1).Conclusion:(1) All groups could reduce the magnitude of TC. The optimal combination is the points of spleen, stomach and pericardial meridians+moxibustion+3 periods of treatment;(2) All groups' symptoms of TCM are relieved after the treatment. But the optimal combination is points of Conception Vessel+moxibustion+3 periods of treatment.