The Research On The Central Aortic Pressure Of Hypertension And Prehypertension Groups In County Community

Objective: Using the cross-sectional survey method, to do a comparative study of small sample on both the central aortic pressure parameters of hypertension and prehypertension people , and to provide a basis for epidemiological investigation of large sample populations for further investigation and study groups.Methods: Through a standard form of questionnaire survey to collect age, sex, weight, hight as well as other baseline information , information on cardiovascular risk factors and quantitative data classification, screening 613 survey of the hypertension and prehypertension people older than 18 years among the authority population in Ping Yuan county Shandong Province. Establishing a single and combinations Syndrome among the hyperactivity of liver yang , accumulation of phlegm-dampness , simultaneous deficiency of Yin and Yang and excess of yang due to deficiency of Yin as the standard sub-type according to the "Chinese medicine clinical research guiding principles". Using non-invasive detection device to measure the central aortic pressure to compare the central aortic pressure parameters in different syndromes . Results:⑴The distribution of common syndromes of hypertension in order are the excess of yang due to deficiency of Yin(124/375),the hyperactivity of liver yang (112/375), simultaneous deficiency of Yin and Yang(76/375), the other four symptoms of the sample size constitutes a relatively small share , so they are not yet confirmed the clinical significance of the constituent ratio.⑵The distribution of common syndromes of prehypertension people is the hyperactivity of liver yang(64/127), excess of yang due to deficiency of Yin(44/127), the other three symptoms of the sample size constitutes a relatively small share , so they are not yet confirmed the clinical significance of the constituent ratio.⑶When the prehypertension group was compared with the hypertensive group , the age , pulse pressure , BMI , WHR and sex of the baseline data have significant differences(P<0.05), other baseline data has the comparability , matching them to eliminate their impact on central aortic pressure parameters between the two groups before testing the center arterial pressure parameters⑷The cSBP , AI , AI P75 of the prehypertension group and the hypertensive group have significant differences(P<0.05);the rise of AI,AI P75 in the prehypertension group with the syndrome of excess of yang due to deficiency of Yin and the hyperactivity of liver yang has significant difference(P<0.05); the cSBP,AI,AI P75 of the hyperactivity of liver yang in both hypertension and prehypertension group have significant difference(sP<0.05). Conclusion: The main two types of syndrome are the hyperactivity of liver yang and excess of yang due to deficiency of Yin , there are obvious rise in the central aortic pressure parameters of"excess of yang due to deficiency of Yin"among the prehypertension people , suggesting the elasticity of arterial decreased significantly.