A Clinical Study On The Effect Of Herbal Fumigation And Washing In Treating Kee Osteoarthritis

Objective:By observing the herbal fumigation and washing pescription Gubi Tang on knee osteoarthritis clinical effect, explore its effective mechanism, provide clinical bases and theories foundations,so as to find a theoretical basis for medical treatment to Kee OteoarthritisMethod:integrates the standard and the elimination standard according to case of illness, chooses 60 knee joint osseous arthritis patient,equally divides into the experimental group and the control group randomly, The experimental group patients use Gubi soup to fumigate and wash knee, rubbing the affected area properly 20 minutes every time, twice a day(morning and evening),while giving a placebo oral Voltaren, three times a day. a tablet(25mg) each time.The control group patients were given oral Voltaren tablets 25mg(Specifications:25mg per tablet), three times a day. while giving the medicine placebo to fumigate and wash knee, the same way with the experimental group.Both groups are treated half month (fifteen days), according to pain,swelling,tenderness and gain to comprehensively score before treatment and after treatment of fifteen days respectively.Both groups are extracted Liquid from knee joint to determine IL-1 levels and recorde the improvement rate of clinical symptoms. the data uses the SPSS 13.0 statistics software to carry on the statistical analysis.Result:In experimental group 30 example patients, the total effectiveness is 90. 0 %; In the control group 30 example patients, the total effectiveness is 63.3%. Two groups of total curative effects after statistics processing P<0.05 have the significance difference. experimental group symptom scores reduces after treatment compared with the previous, processing the P<0.05 after statistics, there is significant difference. control group reduces fewer than before,the statistical P<0.05, there is significant difference. the difference between symptom scores after treatment compared two groups by statistical analysis P<0.01; the reduction of IL-1 of synovial fluid after treatment than before in experimental group, the statistical P<0.01, there is significant difference: the control group after treatment in the synovial fluid IL-1 less than before, the statistical P<0.01, After treatment, IL-1 in synovial fluid compared by the statistical difference P<0.01, there are significant differences.the significant difference of synovial fluid IL-1 can be considered the experimental group superior to the control group; After two groups of case of illness treat the medication security to compare the difference non—statistics significance.Conclusion:1. Pescription of gubitangxunxi can improve condition of patients of knee osteoarthritis, improve the quality of life, and have features of few side effects,Security and non-invasive, The total effect of the experimental group is superior to the control group (P<0.05).2. Prescription of gubitangxunxi can low cytokine level (IL-1) of the joint fluids of the KOA patients.