Clinical Application Evaluation Research On "Wind Cough" By ChaoEnXiang Professor

Background"Wind cough", as early as in the "Book of Rites"in there"......the country that season Xia Xingchun windy cough, "the record; "to treat patients of cough Zhuhou"discourse is the ten of their cough is one of the Feng Xie Cough caused by lung, said:"Wind cough, cough due to statement language may not actually have. ". Vision loss lung, airway spasm of its main pathogenesis. The incidence of the disease throughout the year are to progress to more winter and spring, can occur at any age, a high incidence of children, and middle-aged women were more common. Clinically, the paroxysmal cough, throat itching, shortness of breath, less sputum or no sputum is the main symptom, with paroxysmal, spasmodic, chronic persistent and recurrent features. WESTERN on called "cough variant asthma (Cough variant asthma, CVA) ", is a special type of asthma, can develop into typical asthma. In recent years, due to air pollution and changes in diet and many other factors, the incidence rate showed an increasing trend. This study was designed randomized, controlled, blinded (single blind) a prospective clinical trial study, based on the Sino-Japanese Friendship Hospital, Beijing, Professor Chao Enxiang famous Chinese medicine experts summed up years of clinical practice, the wind cough cough side treatment of the experience of the wind To observe the party (composed of:Sunburn ephedra, almond, asters, Peucedanum, free oneself, to Long, Buff, Schisandra, Sunburn loquat leaf, perilla seed, sage, etc.) on the "wind cough, " Evaluation of the clinical efficacy and related To promote traditional Chinese medicine clinical research on wind and treatment of cough and further development.ObjectiveObserved wind cough cough variant asthma side on the clinical curative effect, and to make scientific assessments, rich methods of Chinese medicine to treat the disease and its application of the mechanism to be explored.MethodGuangdong Provincial Hospital for treatment of Respiratory Medicine at the clinic and meet the criteria of this study wind cough (Feng Xie Fanfei type) were enrolled, a simple random method,40 patients were divided into treatment group and control group, each 20 cases. One control group was given oral Montelukast+theophylline, drug treatment group were based on the additional service of the Chao wind cough side treatment for a total of 21 days, detailed record of changes in the observed indicators, the establishment of a database, Organize data, using SPSS 16.0 software for statistical analysis, a scientific evaluation.Results1. Clinical symptoms:overall symptoms than the two groups before treatment, all patients improved, but the experimental group in reducing cough frequency and degree of patients than the control group, the difference was significant (P<0.05); patients in remissionthroat itching, shortness of breath and phlegm and other symptoms, the two groups rather, there is no significant difference (P>0.05).2.TCM syndromes:the total effective rate in experimental group and markedly effective rate was 90.0%,60.0% in the control group were 75.0%,25.0%. The total effective rate between the two groups there is no significant difference(P>0.05), and markedly effective rate was significant difference(P<0.05).3. Lung function:the experimental group before treatment of various pulmonary function parameters were significantly improved, there were significant differences (P<0.05); control group, FEF25, FEF50, FEF75 and MMEF75/25 and other indicators of small airway function reflect more before treatmentsignificantly reduced, there was significant difference (P<0.05), while both FEV1 and PEF reflect airway function parameters slightly improved compared with before treatment, but no significant difference (P>0.05). Comparison between the two groups found in FEF25, FEF50, FEF75 and other indicators reflecting the improvement of small airway function, the experimental group than the control group, with significant differences (P<0.05). In general, the experimental group on the improvement of lung function in patients with more effective.ConclusionThe wind cough for treatment wind cough is effective, not only to significantly reduce the degree of cough frequency and cough symptoms, but can significantly improve small airway function. Overall, the recent effective than western medicine alone, with no adverse reactions occur, the clinical curative effect.