| ObjectivesPolycystic ovary syndrome PCOS is the most common endocrine and metabolic gynaopathy, which causes women in child-Bearing age endocrinopathy and anovular infertility. It's also a disease with characteristics of High heterogeneity, Multi-factorial paroxysm and Clinical manifestations of polymorphism. The causes of PCOS are still unidentified so that radical therapy can not be found. On the other hand, the advantages of TCM as systematic perspectives, Syndrome Differentiation, multi-systematical regulation and multi-targets effects may bring us another possibility for settling this problem.The pathogenesis of PCOS mostly appears as the hybrid dysfunction of kidney, liver and spleen. RD is its basic pathogenesis. To improve RD patients' symptoms, reduce acne, achieve nomality of menstrual periods, recover ovulation and enhance pregnancy, the paper has symtematically done a lot clinical observation and research on curing Kideny-Deficiency PCOS by PTTCM. To study therapeutic mechanism of TCM towards PCOS from macroscopic perspective and provide clinical and practical reference.Methods50 qualified Patients were randomly placed into two groups. At the same time, the two were respectively named as the Treatment Group (hereinafter referred to as TG) and the Control Group (hereinafter referred to as CG). TG was treated by PTTCM. CG was treated by using Oral Clomiphene Citrate and injecting muscle with HCG Therapy. The two were both taken 3-month menstrual cycle as an observation course. Before treatment and after 3-month menstrual cycle; the two were both taken fasting venous blood to detect horizontal situations of LH, FSH and T; Moreover, Observations were taken in the two for knowing conditions on improvements of RD symptoms and reduction of acne, knowing changes on menstrual disorder and BBT, and knowing changes of ovarian volume and endometrial thickness and conditions of ovulation and pregnancy. Finally, SPSS17.0 software was used to analyzing massive data and information.Results1. Improvement of RD symptoms and acne:Having significant differences by comparasion of the two groups after treatments (P<0.05); treatment group has abvious enhancement after treatment (P<0.05);The control group has no abvious changes and significant differences (P>0.05)2. Improvement of abnormal menstruation and BBT:the two groups both have improvements after treatment (P<0.05); the two groups also have significant differences after treatment (P<0.05)3. Changes of ovarian volume:the two groups both have significant differences (P<0.05); the treatment group has abvious improvement after treatment (P<0.05); the control group has no abvious changes and significant differences (P>0.05)4. Ovulation time and endometrial thickness:In respect of Ovulation time, the two groups have no significant differences (P>0.05). In respect of endometrial thickness, the two groups have significant differences (P<0.05);the treatment has significant differences (P<0.05); the control group has no significant differences (P>0.05)5. Ovulation and pregnancy:In respect of ovulation, the two groups have abvious improvement, and significant differences (P<0.05); the two groups have no significant differences after treatment (P>0.05). In respect of pregnancy, the two groups have significant differences before and after treatment (P<0.05)6. Value changes of serum of LH, FSH, LH/FSH:The two groups both have no significant differences before and after treatnment in respect of values of LH, FSH, LH/FSH (P>0.05). However, Values of T in the two groups have significant differences by comparision after treatment (P<0.05); the treatment has significant differences after treatment (P<0.05);the control group has no significant differences (P>0.05) ConelusionThe paper confirmed that curing PCOS of RD type by PTTCM has obvious curative effects. PTTCM can not only decrease level of T, significantly enhance patient's RD symptoms and physical signs, and establish regular menstruation, but also can promote ovulation and success rate of pregnancy. In terms of clinical effects, PTTCM has many advantages, like instant effects, low recurrence and cost, and no apparent side-effect. In a short, because of its functions of improve reproductive and endocrine and metabolic, TCM is believed to have some research prospects. |