Deng Tietao's Bath Feet On Clinical Observation Of Liver-Yang Hyperactivity Type Of Hypertension And Its Mechanism

ObjectivesTheory of traditional Chinese medicine has a long history outside the government, in the long-term medical practice, clinical experience has accumulated valuable. Deng Tietao Yuzu side is our school's tenured professors, the National Hospital Master Professor Deng Tietao experience side effects of treatment on the human foot by foot contact with the body, and the role of the meridian, blood, organs, blood pressure and improved to The purpose of the symptoms. By combining Chinese and Western treatment of hypertensive patients before and after the blood pressure changes, symptoms and laboratory indicators of change and a simple comparison of the advantages of Western medicine place to explore the side Deng Tietao washes the clinical value of treatment of the disease and the promotion of significance. And investigate the mechanism of the treatment of hypertension for the clinical use of blood pressure control of the party to provide experimental basis for the future lay the foundation for further research and promote traditional Chinese medicine use in the field of hypertension.MethodsSelect Western diagnosis of primary hypertension and the TCM is to observe patients with liver yang object, a prospective single-blind randomized controlled method is used. All patients 80 patients were divided into treatment group and control group,40 patients in each group. Oral antihypertensive drugs in the treatment of Western medicine based on the premise of the treatment group party with Deng Tietao Yuzu Yuzu, the control group were given warm water washes. Blood pressure levels were recorded before and after treatment, treatment for 1 week, Through blood pressure before and after treatment, blood pressure, clinical symptoms, adverse reaction score, the treatment efficiency of the comparative observation, to observe the side Deng Tietao Yuzu clinical efficacy in patients with hypertension; by endothelin before and after treatment of hypertension among the four indicators contrast, the mechanism of its antihypertensive effect.ResultTreatment of hypertension in patients with liver yang in the treatment and control groups in each group before the age, weight, systolic blood pressure, diastolic blood pressure was no significant difference was not significant (P> 0.05). The results showed that after treatment, the treatment group reduced blood pressure (systolic blood pressure difference, diastolic blood pressure values, pulse pressure, mean arterial pressure) than the control group, the antihypertensive effect of significantly between the two groups was statistically significant (P<0.01). The main symptoms were headache, dizziness, insomnia between the two groups before treatment, no statistically significant difference (P> 0.1), a week after treatment, the treatment group, headache, dizziness, insomnia improved significantly in the control group relief is not obvious, the difference was statistically signi ficance (P<0.05). Clinical evaluation criteria based on statistical analysis can be drawn from the treatment group, total effective rate was 95.00% in the control group, the total efficiency of 75.00% in treatment group than the control group (P <0.05).Laboratory indicators, pre-treatment values between groups of ET, the difference was not significant, a week after the review of the treatment of ET between the two groups, the treatment group than the control group decreased, the difference was statistically significant (P<0.05). That treatment of plasma endothelin levels were significantly lower, and its antihypertensive effect may inhibit the endogenous release of vasoconstrictor substances. Four aspects of hypertension, among all groups before treatment aldosterone, renin activity values, the difference was not significant (P> 0.05), treatment week after the review of aldosterone, renin activity between the two groups, the difference was statistically significant (P<0.05). That the treatment group reduced aldosterone secretion and inhibition of renin release is better than the control group. At 4℃and 37℃angiotensin before and after treatment between the two groups, the same group before and after treatment were not statistically significant. ConclusionThe basis of antihypertensive therapy in Western medicine under the premise of Deng Tietao washes before being significantly lower in patients systolic blood pressure, diastolic blood pressure, mean arterial pressure, Significant improvement in clinical symptoms such as headache, dizziness, insomnia, improve patient quality of life. The step-down mechanism may be reduced with the RAS system activity, inhibition of endogenous release of vasoconstrictor substances.