| Objective:To analyze retrospectively the distribution of lower respiratory tract infections pathogens and drug sensitivity, and to provide a reasonable basis on clinical application of antibiotics.Methods:There were 967 hospitalization patients of lower respiratory infections in Lunjiao Hospital in Shunde district, Foshan, from January 2007 to December 2009, whose infections pathogens and drug sensitivity test of pathogens were retrospectively analyzed.Results:There were total 845 cultured bacteria. The positive rate was 87.38%. The Gram staining positive bacteria(G+) were 647 strains (the percentagen of strains was 76.57%), including 162 strains of Staphylococcus epidermidis (19.17%), Staphylococcus hyicus 118 (13.96%), Staphylococcus aureus 71 (8.40%), Staphylococcus auricularis 69 (8.17%), Staphylococcus lugdunensis 52 (6.15%).They were high sensitive to antibiotics such as linezolid, vancomycin. The Gram staining negative bacteria (G-) were 184 strains (the percentagen of strains was 21.78%), including 47 strains of Escherichia coli (5.56%), Los non-Acinetobacter 36 (4.26%), Tatumella ptyseos 28 (3.31%), Pseudomonas aeruginosa 21 (2.49%), Klebsiella pneumoniae 19 (2.25%). They were high sensitive to antibiotics such as imipenem, amikacin, Piperacillin/tazobactam. The cultured fungi were all 14 Candida tropicalis strains, and sensitive to all antifungal agents.Conclusion:The majority of lower respiratory tract infections in our hospital are still Gram-positive bacteria. It is very important to provide a sputum sample for bacteria timely, correctly and normatively, and strengthen the implementation of quality control standards in bacteriolog-ical laboratory. In the absence of bacterial culture and sensitivity test result, choice of antimicrobial drugs should be based on the pathogenic prevalence of local infections, pathogenic characteristics and results of drug sensitivity in order to treat timely and gain a good initial experience of therapy. |
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