| [Objective]1. The main objective is to determine the changing tendency of the quality of life after surgical treatment.2. The main objective is to determine the influence of the course of disease on corrective surgery and quality of life (QoL) of adolescents with idiopathic scoliosis.3. To analyze the quality of life in the postoperative adolescent idiopathic scoliosis patients with infection.[Methods]1.62 AIS patients who were treated with surgery. They were tested A (preoperatively) and at B (within 4 months), C-(5-8 months), D-(9-16 months), and E-(22-36months) using the SRS-22 outcomes questionnaire. The parameters between the two groups were compared with statistic methods, taking P<0.05 as a significant standard.2.110 AIS patients who were treated with surgery were separated into two groups(Short course of disease, long course of disease).The gender, Lenke grouping and major curve Cobb angle between two groups were identical or resemble. Various radiographic measurements preoperative, immediate postoperative, and after 2 years postoperative were compared between the two groups, as well as some other index, such as fusion level, perioperative parameters and SRS-22 outcome instrument.3. From 2007/1 to 2007/12 in our hospital,210 postoperative AIS patients were separated into two groups (infected or non-infected), following up at least 2 years. The parameters in the case records were collected and analyzed in detail, including preoperative, immediate postoperative, and after-2-year postoperative radiographic measurements, and SRS-22 outcomes. The parameters between the two groups were compared with statistic methods, taking P<0.05 as a significant standard.[Results]1. Self-image was significantly improved at B and maintained improvement through 24 months. Function was significantly decreased at A, but returned to baseline by 6 months. Pain was significantly worse at 3 months but was significantly less at 6,12 and 24 months when compared to 3 months.2. The preoperative Cobb angle of the major curve were similar, but the flexibility of the major curve averaged 55.7%in the S and 48.1%in the L group (P=0.034). Preoperative Cobb angles of the minor curve were larger in L group than that in S group(30.1 in the S group and 34.8 in the L group, P=0.035). There was significant difference between the 2 groups for number of fused vertebrae(P=0.027). And Group L demonstrated significantly lower scores in the satisfaction of management domain(P=0.037,L:3.7±0.78 vs. S:4.0±0.70).3. Among 210 patients,9 (4.2%) suffered an infection. There were three acute (15 days postoperative) and 6 delayed (average 35.2 months postoperative) infected patients. The main clinical manifestation included back pain (7 of 9).. local swelling (5 of 9) and incision exuding (4 of 9).3 infected patients were treated with surgery, such as irrigation by putting catheters, debridement and implants removal, besides 4-8 weeks'intravenous antibiotics. Compared with the non-infected patients, those with infection had a lower percent curve correction (P＜0.05). There were no significant differences in the aspects of pain, function, self-image, or mental health of SRS-22 outcomes between the two groups (P>0.05). The infection group had a lower score in the aspect of satisfaction of SRS-22 outcomes compared with non-infection (P＜0.05).[Conclusion]1. The SRS-22 questionnaire is responsive to changes in the postsurgical period. Surgical treatment is the best methods of therapy to AIS.2. The flexibility of the curve was decreased with the increasing course of disease, and the latter may be a risk factor of the minor curve's improving, long course of disease contribute to the increased number of fused vertebrae.3. The complication of infection after surgery of idiopathic scoliosis can be cured with irrigation by putting catheters, debridement and implants removal, combined with a course of antibiotics. However, lower curve correction could be achieved in the infected patients, and the satisfaction with the therapy in these patients reduced.
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