Discussion On The Relationship Between Mycoplasma Pneumoniae Infection And Acute Urticaria In Children

objectiveTo explore the relationship between mycoplasma pneumoniae infection and acute urticaria in children, and the possible pathogenesis.Materials and MethodsChoose 106 children with acute urticaria of unknown etiology, including male 60 and female 46, age from 2 to 14 years old (average 4.88 years old). At the same time Select 100 Hospitalized patients in the same period without allergic disease as control, including male 52 and female 48, age from 2 to 14 years old (average 4.27 years old). The MP-Ab level and total serum IgE level of the two groups were tested by "passive particle agglutination" and "ACCESS Immune analysis system" respectively.ResultsMP infection rates of acute urticaria in children was higher than that in control, there was significant difference between two groups (X2=13.91, p<0.01); There was no significant differences between acute urticaria with fever or respiratory symptoms and acute urticaria without respiratory symptoms in MP infection rates; Total serum IgE level of acute urticaria in children with MP infection were significantly lower than that without MP infection(t=2.68, p<0.01); Total serum IgE level of acute urticaria in children with MP infection were no significant differences from control. Conclusions1. MP infection was closely related to acute urticaria in children. For unknown etiology of acute urticaria in children, Regardless of whether fever or respiratory symptoms, We should eliminate the possibility of MP infection.2. the pathogenesis of the acute infection related MP urticaria may not be mediated by IgE type allergy.