Clinical Studies On Serum Cytokines And Leptin Level In Children With Mycoplasma Pneumoniae Pneumonia

Mycoplasma pneumoniae (MP) is a pathogen of Mycoplasma Pneumoniae Pneumonia in children. It can not only cause the respiratory infection, but also induce the extrapulmonary manifestation. After mycoplasm pneumoniae enters respiratory tract, one side it adheres to epithelial cell closely which causes damage to epithelium mucosae and presents symptoms. On the other side, acting as a external antigen it can stimnlate body immune system to produce immune response and occur the disturbance of cellular immunity and humoral immuneity. Some study indicated that the incidence of Mycoplasma Pneumoniae Pneumonia (MMP) in children has increased in recent years. MPP is more than 30 percent in respiratory infection in children. MMP is one most common pneumonia happened in school child and adolescent period, and also considerable in infant period. The morbidity has goen up in infant period year by year. The mechanism of MPP has not been clarified, immune response and MP adhension to airway epithelial cell may be involved in the mechanism. Some study indicated that Cytokines play an important role in the immune mechanism interaction between immune cells.Recently, some studies indicated that Leptin receptor could be detected in immune system. The"leptin-cytokine"theory considered...