| Objective: By comparing the IVF-ET pregnancy and in spontaneous pregnancy (1) Infant gestational age at birth, weight, length, 1 minute after birth and 10-minute Apgar score; (2) premature children and the incidence of low birth weight children; (3) The incidence of postpartum hemorrhage; (4) pregnant third trimester complications (oligohydramnios, premature rupture of membranes, pregnancy induced hypertension, abnormal glucose tolerance during pregnancy and fetal distress) were recorded. Analysis and evaluation of IVF-ET pregnancy pregnant women and perinatal outcome of fetal safety.Methods: Select the Center for Reproductive Medicine in our hospital received conventional in vitro fertilization - embryo transplantation and successful pregnancy in January 2003 to October 2009 obstetric deliveries in our hospital 112 cases of pregnant women for the study group (A group). Select natural pregnancy with obstetric delivery in our hospital and a similar delivery time, 152 cases of pregnant women as control group (B group). Other factors between the two groups (pregnant women, age, height, weight and other perinatal period) showed no significant difference. Delivery by cesarean section: A group in 90 cases, of which 48 cases were single births: the baby was delivered 27, girls 21; twins were 22 cases of birth: the baby was delivered 49, girl 35. B 120 patients, of which 76 cases were single births: the baby was delivered 48, 28 girls; twin birth in 44 cases: 46 baby boy was delivered, the baby 42. Natural Childbirth: A group of 22 cases, all single births, the baby was delivered 7, girls 15. B 32 cases, all single births, the baby was delivered 18 months, girls 14. There were no stillbirths and neonatal deaths. And compared: 1.A, B groups of cesarean section and natural products of single births and twin male and female newborns of gestational age (w), weight (g), length (cm), 1-minute after birth and 10-minute Apgar score values. 2.A, B and natural products cesarean section group, one fetus and premature infant twin children and the incidence of low birth weight children. 3.A, B two sets of single, twin pregnant women, the incidence of postpartum hemorrhage. 4.A, B two sets of single, pregnant women, perinatal twin oligohydramnios, premature rupture of membranes, pregnancy induced hypertension, gestational impaired glucose tolerance and the incidence of fetal distress.Results: 1.A, B groups Neonatal gestational age at birth (w), weight (g), length (cm), 1 minute after birth and 10-minute Apgar score of the comparison shows: 1.1.A, B groups single-birth by cesarean section boy's gestational age(38.18±1.78 VS 39.42±1.82), weight(3078.52±509.95 VS 3263.38±521.45), length(50.04±3.12 VS 51.62±2.53), 1-minute Apgar score(9.19±1.33 VS 9.66±0.68),10- minute Apgar score(9.93±0.38 VS 9.97±0.18), the difference was not statistically significant (p> 0.05).Two groups single-birth by cesarean section girl's gestational ag(e37.85±1.58 VS 39.24±1.36), weight(3049.52±666.38 VS 3143.51±402.34), length(49.76±3.36 VS 50.47±1.42), 1-minute Apgar score( 8.76±1.92 VS 9.65±0.83),10- minute Apgar score(9.62±1.32 VS 10.00±0.00), the difference was not statistically significant (p> 0.05). 1.2. Two groups of twin cesarean section boy's gestational age(36.39±1.59 VS 36.75±1.69), weight(2432.04±399.17 VS 2402.90±381.24), length(46.88±2.67 VS 46.79±2.89), 1-minute Apgar score(9.39±0.91 VS 9.18±1.29),10- minute Apgar score(9.90±0.47 VS 9.98±0.18), the difference was not statistically significant (p> 0.05). two groups of twin cesarean section girl's gestational age(35.82±2.27 VS 36.98±1.83), weight(2250.57±425.97 VS 2343.85±420.04), length(45.77±2.91 VS 46.31±3.72),1-minute Apgar score(9.11±1.11 VS 9.18±1.37),10- minute Apgar score(9.86±0.55 VS 9.88±0.44), the difference was not statistically significant (P> 0.05).1.3. Two groups natural produced a single child boy's gestational age(37.57±2.26 VS 38.98±1.57), weigh(t2863.71±419.92 VS 3120.04±538.42), length(49.57±2.94 VS 51.24±2.68),1-minute Apgar score(9.14±2.27 VS 9.58±1.32),10-minute Apgar score(9.86±0.38 VS 10.00±0.00), the difference was not statistically significant (P> 0.05). Two groups natural produced a single child girl's gestational age(38.37±1.66 VS 39.28±2.45), weigh(t2918.67±406.02 VS 3104.76±446.32), length(50.33±2.66 VS 51.24±2.31),1-minute Apgar score(9.33±1.76 VS 9.29±0.76),10 -minute Apgar score(10.00±0.00 VS 10.00±0.00), the difference was not statistically significant (p> 0.05).2. A, B two groups of premature children, the incidence of low birth weight children in the comparison:2.1. Caesarean section was delivered single births: A group of 48, B group 76, of which 9 A group of preterm children (incidence rate 18.8%), low birth weight children 7 (incidence rate 14.6%); B group 8 preterm children (incidence rate 10.5%), low birth weight children 3 (incidence rate 3.9%). There was no significant difference between two groups (p> 0.05).2.2. Caesarean section was delivered twins: A group of 84, B group 88, in which A group of 42 preterm children (incidence rate 50%), 49 low birth weight children (incidence rate 58.3%); B group 40 premature children (incidence rate 45.5%), low birth weight in 46 children (incidence rate 52.3%). There was no significant difference between two groups (p> 0.05).2.3. Natural delivery of single fetus: A group of 22, B group 32, in which A group of premature children 3 (incidence 13.6%), low birth weight children 3 (incidence rate 13.6%); B group of premature children 4 ( rate was 12.5%), low birth weight children 2 (incidence rate 6.3%). There was no significant difference between the two groups (p> 0.05).3. A, B group compared the incidence of postpartum hemorrhage:3.1. Deliveries were single births, A group of 70 cases, B group 108 cases, of which A group of postpartum hemorrhage in 2 cases (incidence rate 2.9%); B group 7 cases of postpartum hemorrhage (incidence rate 6.5%). The difference was not statistically significant (p> 0.05).3.2. Deliveries were twins: A group of 42 cases, B group 44 patients, of which A group of postpartum bleeding in 6 cases (incidence rate 14.3%); B group 7 cases of postpartum hemorrhage (incidence rate 15.9%). No significant difference between the two groups (p> 0.05).4. A, B two groups of pregnant women, pregnancy complications (oligohydramnios, premature rupture of membranes, pregnancy induced hypertension, abnormal glucose tolerance during pregnancy and fetal distress) Comparison of the incidence of4.1. A, B two groups of pregnant women during pregnancy incidence of oligohydramnios compared to 4.1.1. Single births are: A group of 70 cases, B group 108 cases, of which A group of oligohydramnios in 7 cases (incidence rate 10%); B 5 cases of oligohydramnios group (incidence rate 4.6%). No significant difference between the two groups (p> 0.05). 4.1.2. Twin parturition: A group of 42 cases, B group 44 patients, of which A group of oligohydramnios in 1 (incidence rate 2.4%); B group oligohydramnios in 2 cases (incidence rate 4.5%). No significant difference between the two groups (p> 0.05).4.2. A, B two pregnant women, the incidence of premature rupture of membranes compared to 4.2.1. Single births are: A group of 70 cases, B group 108 cases, of which A group of 11 patients with premature rupture of membranes (incidence rate 15.7%) ; B group of premature rupture of membranes, 13 cases (incidence rate 12.0%). No significant difference between the two groups (p> 0.05). 4.2.2. Twin parturition: A group of 42 cases, B group 44 patients, including premature rupture of membranes A group of 10 patients (incidence rate 23.8%); B group of premature rupture of membranes in 8 cases (incidence rate 18.2% ). No significant difference between the two groups (p> 0.05).4.3. A, B two groups of pregnant women, perinatal diseases, the incidence of pregnancy-induced hypertension compared to 4.3.1. Single births are: A group of 70 cases, B group 108 cases, of which A group of hypertensive disorders of pregnancy in 8 cases (incidence rate 11.4%); B group pregnancy hypertension in 5 patients (incidence rate 4.6%). No significant difference between the two groups (p> 0.05). 4.3.2. Twin parturition: A group of 42 cases, B group 44 patients, of which A group of 9 cases of pregnancy induced hypertension (incidence rate 21.4%); B group of hypertensive disorders of pregnancy in 18 cases (incidence rate 40.9% ). No significant difference between the two groups4.4. A, B two sets of maternal perinatal incidence of gestational impaired glucose tolerance compared to 4.4.1. Single births are: A group of 70 cases, B group 108 cases, of which A group of 9 cases of gestational impaired glucose tolerance (the incidence of to 12.9%); B group 7 cases of gestational impaired glucose tolerance, (incidence rate 6.5%), no significant difference between the two groups (p> 0.05). 4.4.2. Twin parturition: A group of 42 cases, B group 44 patients, of which A group of 11 patients with gestational impaired glucose tolerance (incidence rate 26.2%); B 5 cases of gestational impaired glucose tolerance group (incidence rate 11.4%). No significant difference between the two groups (p> 0.05).4.5. A, B two groups of pregnant women, the incidence of fetal distress during pregnancy compared to 4.5.1. Single births are: A group of 70 cases, B group 108 cases, of which A group of 9 cases of fetal distress (incidence rate 12.9%); B group 6 cases of fetal distress (incidence rate 5.6%). No significant difference between the two groups (p> 0.05). 4.5.2. Twin parturition: A group of 42 cases, B group 44 patients, of which A group of 6 cases of fetal distress (incidence rate 14.3%); B 7 cases of fetal distress group (incidence rate of 15.9%). No significant difference between the two groups (p> 0.05).Conclusion: 1. IVF - pregnancy childbirth birth gestational age, weight, height and Apgar score of newborns with similar birth natural pregnancy.2. In vitro fertilization - embryo transfer pregnancy premature children, children with low birth weight rates are higher than the natural pregnancy, but without significant difference.3. In vitro fertilization - embryo transfer and natural pregnancy pregnant women similar to the incidence of postpartum hemorrhage.4. In vitro fertilization-embryo transfer pregnancy occurred perinatal oligohydramnios, pregnancy induced hypertension, fetal distress, similar to the rate of natural pregnancy. The occurrence of premature rupture of membranes, gestational impaired glucose tolerance in pregnancy rates are higher than the natural tendency, but no significant difference. |
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