Efficacy Of Pentazocine For Patient-controlled Intravenous Analgesia In Patients' Underging Operation Of Gallbladder.

Objective:To observe the effect of Pentazocine for patient-controlled intravenous analgesia (PCIA) in patients' underging operation of gallbladder.Methods:Sixty patients underging operation of gallbladder,ASAⅠ-Ⅱ.Sixty cases were divided randomly into two groups:group P and group F with 30 cases each.The group P and group F were given PCIA after operations.Group P contained Pentazocine 180mg,Ondanosetron 8mg in 100ml physic liquor,and the other was Sodium Chloride.Group F contained Fentanyl 0.8mg,Ondanosetron 8mg in 100ml physic liquor,and the other was Sodium Chloride.The effect of analgesia at 2,4,8,12,24,48 h after operation and the side effects such as nausea,vomiting in the two groups will be recorded.And the satisfactory degree of patients will be recorded at 48 h.Result:The VAS of two groups were similar at rest.The VAS values of group F at 4 and 8 h after operation were significantly higher than those of group P on exertion(all P＜0.05),which became similar when at rest.The time required for supplemental bolus in group F was significantly higher than that of group P(P＜0.05).The degrees of sedation and the incidences of nausea and vomiting in group F were higher than those of goup P(P＜0.05).The satisfactory degree of patients in the two groups were similar.(P＞0.05).Conclusion:Pentazocine has satisfactory effects of postoperative analgesia,compared with Fentanyl;the effects of adverse were lower.