Clinical Research On Efficacy Of Acute Exacerbations Of Chronic Obstructive Pulmonary Disease (AECOPD) With Suzi Jiangqi Decoction

OBJECTIVEThe aim of the study was to assess the effect of Suzi Jiangqi decoction on AECOPD by analyzing the symptom,sign,blood gas analysis.METHOD60 AECOPD patients(stageâ… -â…¢) with retention of Phlegm and Heat Syndrome in the Lung were randomly assigned to the treating group or to the control group.The treating group accept conventional therapy of the western medicine(Controllability oxygen treatment,bronchodilators,antibiotic,expectorants)plus Suzi Jiangqi decoction,while the control group purely accepted conventional therapy of the western medicine.The course was 10 days.The clinical symptoms and sign,blood gas analysis were observed and compared after 10 days.RESULTS1.The management of Suzi Jiangqi decoction could improve the clinical symptoms and sign of COPD patients.The clinical symptoms and sign of both group have significant difference after ten-day treatment compared with the clinical symptoms and sign before the treatment(p＜0.05或p＜0.01).The clinical symptoms and sign of the treating group was better than the control group with significant difference(p＜0.05或p＜0.01) after the treatment,which showed the management of the treating group is better. 2.The management of Suzi Jiangqi decoction could remedy the state of anoxia and carbon dioxide retention.PaO₂ and PaCO₂ of each group have significant difference(p＜0.05) after the treatment compared with pre-treatment,that showed the managements of both groups could improve PaO₂ and reduce PaCO₂.After the treatment,PaO₂ and PaCO₂ of the treating group is better than the control group,with significant difference(p＜0.05)CONCLUSIONSThe management of the Suzi Jiangqi decoction can help AECOPD patients,it can improve the clinical symptoms and sign,remedy the state of anoxia and carbon dioxide retention.